The demand for sustainable and environmentally friendly sources of foods and cosmetics is
increasing owing to concerns about the rapid growth of the global population and climate …

Highlights•Microbial cell factories are becoming important in sustainable chemical
production.•Systems metabolic engineering allows efficient microbial cell factory …

While academic‐level studies on metabolic engineering of microorganisms for production of
chemicals and fuels are ever growing, a significantly lower number of such production …

Metabolic engineering can have a pivotal role in increasing the environmental sustainability
of the transportation and chemical manufacturing sectors. The field has already developed …

Industrial strain development requires system-wide engineering and optimization of cellular
metabolism while considering industrially relevant fermentation and recovery processes. It …

Metabolic engineering allows development of microbial strains efficiently producing
chemicals and materials, but it requires much time, effort, and cost to make the strains …

Metabolic engineering aims to improve the production of economically valuable molecules
through the genetic manipulation of microbial metabolism. While the discipline is a little over …

Global shift to sustainability has driven the exploration of alternative feedstocks beyond
sugars for biomanufacturing. Recently, C1 (CO2, CO, methane, formate and methanol) and …

Cell factories have been largely exploited for the controlled production of substances of
interest for food, pharma and biotech industries. Although human-controlled microbial …

Recent advances in metabolic engineering enable the production of high-value chemicals
via expressing complex biosynthetic pathways in a single microbial host. However, many …