Chronic electroencephalography in epilepsy with a responsive neurostimulation device: current status and future prospects

VR Rao - Expert Review of Medical Devices, 2021 - Taylor & Francis
Introduction Implanted neurostimulation devices are gaining traction as therapeutic options
for people with certain forms of drug-resistant focal epilepsy. Some of these devices enable …

[HTML][HTML] Under-sampling in epilepsy: limitations of conventional EEG

MO Baud, K Schindler, VR Rao - Clinical neurophysiology practice, 2021 - Elsevier
The cyclical structure of epilepsy was recently (re)-discovered through years-long
intracranial electroencephalography (EEG) obtained with implanted devices. In this review …

[HTML][HTML] Resting-state background features demonstrate multidien cycles in long-term EEG device recordings

WKS Ojemann, BH Scheid, S Mouchtaris, A Lucas… - Brain Stimulation, 2023 - Elsevier
Background Longitudinal EEG recorded by implanted devices is critical for understanding
and managing epilepsy. Recent research reports patient-specific, multi-day cycles in device …

Early detection rate changes from a brain‐responsive neurostimulation system predict efficacy of newly added antiseizure drugs

IH Quraishi, MR Mercier, TL Skarpaas, LJ Hirsch - Epilepsia, 2020 - Wiley Online Library
Objective Brain‐responsive neurostimulation (RNS System, NeuroPace) is used to treat
medically refractory focal epilepsy and also provides long‐term ambulatory …

A new era in electroencephalographic monitoring? Subscalp devices for ultra–long‐term recordings

J Duun‐Henriksen, M Baud, MP Richardson… - …, 2020 - Wiley Online Library
Inaccurate subjective seizure counting poses treatment and diagnostic challenges and thus
suboptimal quality in epilepsy management. The limitations of existing hospital‐and home …

The RNS System: brain-responsive neurostimulation for the treatment of epilepsy

B Jarosiewicz, M Morrell - Expert Review of Medical Devices, 2021 - Taylor & Francis
Introduction: Epilepsy affects more than 1% of the US population, and over 30% of adults
with epilepsy do not respond to antiseizure medications without life-impacting medication …

A rational approach to understanding and evaluating responsive neurostimulation

ND Sisterson, TA Wozny, V Kokkinos, A Bagic… - Neuroinformatics, 2020 - Springer
Closed-loop brain stimulation is increasingly used in level 4 epilepsy centers without an
understanding of how the device behaves on a daily basis. This lack of insight is a barrier to …

Intracranial electroencephalographic biomarker predicts effective responsive neurostimulation for epilepsy prior to treatment

BH Scheid, JM Bernabei, AN Khambhati… - …, 2022 - Wiley Online Library
Objective Despite the overall success of responsive neurostimulation (RNS) therapy for drug‐
resistant focal epilepsy, clinical outcomes in individuals vary significantly and are hard to …

Wearable electroencephalography for ultra-long-term seizure monitoring: a systematic review and future prospects

JM Nielsen, D Rades, TW Kjaer - Expert Review of Medical Devices, 2021 - Taylor & Francis
Introduction Wearable electroencephalography (EEG) for objective seizure counting might
transform the clinical management of epilepsy. Non-EEG modalities have been validated for …

[HTML][HTML] Acute effects of brain-responsive neurostimulation in drug-resistant partial onset epilepsy

SN Rønborg, R Esteller, TK Tcheng, DA Greene… - Clinical …, 2021 - Elsevier
Objective Understanding the acute effects of responsive stimulation (AERS) based on
intracranial EEG (iEEG) recordings in ambulatory patients with drug-resistant partial …