2-Amino-1, 3, 4-thiadiazole as a potential scaffold for promising antimicrobial agents
G Serban, O Stanasel, E Serban… - Drug design, development …, 2018 - Taylor & Francis
Pathogenic microorganisms are causative agents for different types of serious and even
lethal infectious diseases. Despite advancements in medication, bacterial and fungal …
lethal infectious diseases. Despite advancements in medication, bacterial and fungal …
An overview of the synthesis and antimicrobial, antiprotozoal, and antitumor activity of thiazole and bisthiazole derivatives
Thiazole, a five-membered heteroaromatic ring, is an important scaffold of a large number of
synthetic compounds. Its diverse pharmacological activity is reflected in many clinically …
synthetic compounds. Its diverse pharmacological activity is reflected in many clinically …
Synthesis and biological evaluation of 2‐mercapto‐1, 3‐benzothiazole derivatives with potential antimicrobial activity
C Franchini, M Muraglia, F Corbo… - … der Pharmazie: An …, 2009 - Wiley Online Library
The enhancement of bacterial resistance of pathogens to currently available antibiotics
constitutes a serious public health threat. So, intensive efforts are underway worldwide to …
constitutes a serious public health threat. So, intensive efforts are underway worldwide to …
Synthesis of some new 2-(3-pyridyl)-4, 5-disubstituted thiazoles as potent antimicrobial agents
As a part of ongoing studies in developing new potent antimicrobial agents, a series of novel
2-(3-pyridyl)-4, 5-disubstituted thiazoles was efficiently synthesized and characterized by …
2-(3-pyridyl)-4, 5-disubstituted thiazoles was efficiently synthesized and characterized by …
[PDF][PDF] Thiazoles: a valuable insight into the recent advances and biological activities
Thiazoles displayed broad range of biological activities and found in many potent
biologically active molecules such as Sulfathiazol (antimicrobial drug), Ritonavir …
biologically active molecules such as Sulfathiazol (antimicrobial drug), Ritonavir …
Bioactive thiazole and benzothiazole derivatives
The heterocycles are the versatile compounds existing in almost all natural products and
synthetic organic compounds, usually associated with one or the other biological activity …
synthetic organic compounds, usually associated with one or the other biological activity …
Synthesis and evaluation of 4-amino-5-phenyl-4H-[1,2,4]-triazole-3-thiol derivatives as antimicrobial agents
PK Sahoo, R Sharma, P Pattanayak - Medicinal chemistry research, 2010 - Springer
Abstract A series of novel 1, 2, 4-triazole derivatives have been synthesized by condensing
the methyl benzoate and methyl salicylate with various substituents; their structures were …
the methyl benzoate and methyl salicylate with various substituents; their structures were …
An overview on synthetic 2-aminothiazole-based compounds associated with four biological activities
M Farouk Elsadek, B Mohamed Ahmed… - Molecules, 2021 - mdpi.com
Amongst sulfur-and nitrogen-containing heterocyclic compounds, the 2-aminothiazole
scaffold is one of the characteristic structures in drug development as this essential …
scaffold is one of the characteristic structures in drug development as this essential …
Synthesis of some new 1, 3, 4-thiadiazol-2-ylmethyl-1, 2, 4-triazole derivatives and investigation of their antimicrobial activities
A Demirbas, D Sahin, N Demirbas… - European journal of …, 2009 - Elsevier
4-Amino-2-[(5-arylamino-4, 5-dihydro-1, 3, 4-thiadiazol-2-yl) methyl]-5-(4-methylphenyl)-2, 4-
dihydro-3H-1, 2, 4-triazol-3-ones (3a–c) were obtained in acidic media via the formation of 2 …
dihydro-3H-1, 2, 4-triazol-3-ones (3a–c) were obtained in acidic media via the formation of 2 …
1, 3, 4-Thiadiazoles: A potent multi targeted pharmacological scaffold
Despite a significant work on thiadiazoles, continuous efforts are still being made to identify
novel heterocyclic compounds with potent biological activities. This review may help the …
novel heterocyclic compounds with potent biological activities. This review may help the …