Porcine models for studying complications and organ crosstalk in diabetes mellitus
The worldwide prevalence of diabetes mellitus and obesity is rapidly increasing not only in
adults but also in children and adolescents. Diabetes is associated with macrovascular …
adults but also in children and adolescents. Diabetes is associated with macrovascular …
[PDF][PDF] Animal models of diabetes mellitus: relevance to vascular complications
CS Thompson - Current pharmaceutical design, 2008 - researchgate.net
The prevalence of diabetes mellitus is increasing worldwide at an alarming rate due to
population growth, obesity, sedentary lifestyle and aging. Consequently, diabetic …
population growth, obesity, sedentary lifestyle and aging. Consequently, diabetic …
Animal models of diabetic macrovascular complications: key players in the development of new therapeutic approaches
SE Heinonen, G Genové, E Bengtsson… - Journal of diabetes …, 2015 - Wiley Online Library
Diabetes mellitus is a lifelong, incapacitating metabolic disease associated with chronic
macrovascular complications (coronary heart disease, stroke, and peripheral vascular …
macrovascular complications (coronary heart disease, stroke, and peripheral vascular …
[HTML][HTML] The Munich MIDY Pig Biobank–A unique resource for studying organ crosstalk in diabetes
A Blutke, S Renner, F Flenkenthaler, M Backman… - Molecular …, 2017 - Elsevier
Objective The prevalence of diabetes mellitus and associated complications is steadily
increasing. As a resource for studying systemic consequences of chronic insulin …
increasing. As a resource for studying systemic consequences of chronic insulin …
Update on animal models of diabetic retinopathy: from molecular approaches to mice and higher mammals
R Robinson, VA Barathi, SS Chaurasia… - Disease models & …, 2012 - journals.biologists.com
Diabetic retinopathy (DR) is the most common microvascular complication of diabetes and
one of the major causes of blindness worldwide. The pathogenesis of DR has been …
one of the major causes of blindness worldwide. The pathogenesis of DR has been …
Comparative aspects of rodent and nonrodent animal models for mechanistic and translational diabetes research
S Renner, B Dobenecker, A Blutke, S Zoels, R Wanke… - Theriogenology, 2016 - Elsevier
The prevalence of diabetes mellitus, which currently affects 387 million people worldwide, is
permanently rising in both adults and adolescents. Despite numerous treatment options …
permanently rising in both adults and adolescents. Despite numerous treatment options …
The use of animal models in the study of diabetes mellitus
A Chatzigeorgiou, A Halapas, K Kalafatakis, E Kamper - In vivo, 2009 - iv.iiarjournals.org
Animal models have enormously contributed to the study of diabetes mellitus, a metabolic
disease with abnormal glucose homeostasis, due to some defect in the secretion or the …
disease with abnormal glucose homeostasis, due to some defect in the secretion or the …
Animal models of type 2 diabetes: clinical presentation and pathophysiological relevance to the human condition
WT Cefalu - ILAR journal, 2006 - academic.oup.com
The prevalence of diabetes throughout the world has increased dramatically over the recent
past, and the trend will continue for the foreseeable future. One of the major concerns …
past, and the trend will continue for the foreseeable future. One of the major concerns …
Animal models of diabetic retinopathy
X Jiang, L Yang, Y Luo - Current Eye Research, 2015 - Taylor & Francis
Diabetic retinopathy (DR) is one of today's main causes of blindness in numerous
developed countries worldwide. The underlying pathogenesis of DR is complex and not well …
developed countries worldwide. The underlying pathogenesis of DR is complex and not well …
Development and application of rodent models for type 2 diabetes
D Chen, MW Wang - Diabetes, Obesity and metabolism, 2005 - Wiley Online Library
The increasing worldwide incidence of diabetes in adults constitutes a global public health
burden. It is predicted that by 2025, India, China and the United States will have the largest …
burden. It is predicted that by 2025, India, China and the United States will have the largest …