The discoveries of cancer research have been translated into the clinical management of
lung cancer patients. So far, the approach of targeted therapy that is directed towards certain …

Lung cancer is the number one cause of cancer-related death in the western world. Its
incidence is highly correlated with cigarette smoking, and about 10% of long-term smokers …

Lung carcinoma is one of the most common human cancers and is estimated to have an
incidence of approximately 2 million new cases per year worldwide with a 20% mortality …

Lung cancer is the leading cause of cancer-related death worldwide with a 5-year survival
rate of less than 15%, despite significant advances in both diagnostic and therapeutic …

Lung cancer is a complex disease composed of diverse histological and molecular types
with clinical relevance. The advent of large-scale molecular profiling has been helpful to …

Context.—Lung carcinoma is the result of sequential accumulation of genetic and epigenetic
changes. Lung adenocarcinoma is a heterogeneous disease with diverse somatic …

This overview of the molecular pathology of lung cancer includes a review of the most
salient molecular alterations of the genome, transcriptome, and the epigenome. The insights …

Lung cancer is the leading cause of cancer-related death in men and women in the United
States, accounting for approximately 28% of total cancer deaths in 2010 despite comprising …

While histopathology has traditionally been the cornerstone of treatment decisions in the
management of lung cancer patients, the complexity and heterogeneity of histological …

Clinical and pathologic staging of lung cancer is suboptimal in achieving the goals of
assessing prognosis and selecting therapy. Although the technologic developments that …