Background Antiretroviral drugs have been shown to reduce risk of mother‐to‐child
transmission of human immunodeficiency virus (HIV) and are also widely used for post …

Background: Recent studies have estimated the reduction in HIV-1 infectiousness with
antiretroviral therapy (ART), but high-quality studies such as randomized controlled trials …

Background Antiretrovirals have substantial promise for HIV-1 prevention, either as
antiretroviral treatment (ART) for HIV-1–infected persons to reduce infectiousness, or as pre …

Background On the basis of the results of the randomised clinical trial HPTN 052 and
observational studies, WHO has recommended that antiretroviral therapy be offered to all …

Background The risk of sexual HIV transmission in serodiscordant couples when the HIV-
positive partner has full virologic suppression on combination antiretroviral therapy (cART) is …

Serodiscordant couples play an important role in maintaining the global HIV epidemic. This
review summarizes biobehavioral and biomedical HIV prevention options for serodiscordant …

Several studies have shown that HIV-1 transmission in serodiscordant couples is
significantly reduced when the plasma viral load (pVL) in the infected partner is low or …

Objectives: To synthesize the evidence on the risk of HIV transmission through unprotected
sexual intercourse according to viral load and treatment with combination antiretroviral …

Objective: To evaluate the impact of antiretroviral therapy (ART) on HIV-1 transmission rates
among HIV-1 discordant couples in Rakai, Uganda. Design: Observational cohort study …

Background Antiretroviral-based interventions for HIV-1 prevention, including antiretroviral
therapy (ART) to reduce the infectiousness of HIV-1 infected persons and pre-exposure …