[HTML][HTML] KSHV infection of B cells primes protective T cell responses in humanized mice
N Caduff, L Rieble, M Böni, D McHugh… - Nature …, 2024 - nature.com
Kaposi sarcoma associated herpesvirus (KSHV) is associated with around 1% of all human
tumors, including the B cell malignancy primary effusion lymphoma (PEL), in which co …
tumors, including the B cell malignancy primary effusion lymphoma (PEL), in which co …
Primary B Lymphocytes Infected with Kaposi's Sarcoma-Associated Herpesvirus Can Be Expanded In Vitro and Are Recognized by LANA-Specific CD4+ T Cells
SM Nicol, S Sabbah, KF Brulois, JU Jung… - Journal of …, 2016 - Am Soc Microbiol
Kaposi's sarcoma-associated herpesvirus (KSHV) has tropism for B lymphocytes, in which it
establishes latency, and can also cause lymphoproliferative disorders of these cells …
establishes latency, and can also cause lymphoproliferative disorders of these cells …
[HTML][HTML] KSHV latency locus cooperates with myc to drive lymphoma in mice
Kaposi sarcoma-associated herpesvirus (KSHV) has been linked to Kaposi sarcoma and B-
cell malignancies. Mechanisms of KSHV-induced oncogenesis remain elusive, however, in …
cell malignancies. Mechanisms of KSHV-induced oncogenesis remain elusive, however, in …
[HTML][HTML] The CD8 and CD4 T-cell response against Kaposi's sarcoma-associated herpesvirus is skewed towards early and late lytic antigens
RC Robey, D Lagos, F Gratrix, S Henderson… - PLoS …, 2009 - journals.plos.org
Kaposi's sarcoma-associated herpesvirus (KSHV) is causally related to Kaposi's sarcoma
(KS), the most common malignancy in untreated individuals with HIV/AIDS. The adaptive T …
(KS), the most common malignancy in untreated individuals with HIV/AIDS. The adaptive T …
Kaposi's sarcoma-associated herpesvirus latency locus renders B cells hyperresponsive to secondary infections
Kaposi's sarcoma-associated herpesvirus (KSHV) induces B cell hyperplasia and neoplasia,
such as multicentric Castleman's disease (MCD) and primary effusion lymphoma (PEL). To …
such as multicentric Castleman's disease (MCD) and primary effusion lymphoma (PEL). To …
[HTML][HTML] Co-infection of the Epstein–Barr virus and the Kaposi sarcoma-associated herpesvirus
M Böni, L Rieble, C Münz - Viruses, 2022 - mdpi.com
The two human tumor viruses, Epstein–Barr virus (EBV) and Kaposi sarcoma-associated
herpesvirus (KSHV), have been mostly studied in isolation. Recent studies suggest that co …
herpesvirus (KSHV), have been mostly studied in isolation. Recent studies suggest that co …
[HTML][HTML] Probing reconstituted human immune systems in mice with oncogenic γ-Herpesvirus infections
C Münz - Frontiers in Immunology, 2020 - frontiersin.org
Mice with reconstituted human immune systems can mount cell-mediated immune
responses against the human tumor viruses Epstein Barr virus (EBV) and Kaposi sarcoma …
responses against the human tumor viruses Epstein Barr virus (EBV) and Kaposi sarcoma …
[HTML][HTML] Natural killer cell responses to human oncogenic γ-herpesvirus infections
C Münz - Seminars in Immunology, 2022 - Elsevier
The two γ-herpesviruses Epstein Barr virus (EBV) and Kaposi sarcoma associated
herpesvirus (KSHV) are each associated with more than 1% of all tumors in humans. While …
herpesvirus (KSHV) are each associated with more than 1% of all tumors in humans. While …
[HTML][HTML] Persistent KSHV infection increases EBV-associated tumor formation in vivo via enhanced EBV lytic gene expression
The human tumor viruses Epstein-Barr virus (EBV) and Kaposi sarcoma-associated
herpesvirus (KSHV) establish persistent infections in B cells. KSHV is linked to primary …
herpesvirus (KSHV) establish persistent infections in B cells. KSHV is linked to primary …
Killing of Kaposi's sarcoma‐associated herpesvirus‐infected fibroblasts during latent infection by activated natural killer cells
NC Matthews, MR Goodier, RC Robey… - European journal of …, 2011 - Wiley Online Library
Kaposi's sarcoma‐associated herpesvirus (KSHV) establishes life‐long infection by evading
clearance by the host immune system. In de novo infection and lytic replication, KSHV …
clearance by the host immune system. In de novo infection and lytic replication, KSHV …