The roles of steroids in zebrafish sex differentiation, gonadal development, and function of
the adult gonad are poorly understood. Herein, we used ferredoxin 1b (fdx1b) mutant …

Mitochondrial cytochrome P450 (CYP) enzymes rely on electron transfer from the redox
partner ferredoxin 1 (FDX1) for catalytic activity. Key steps in steroidogenesis require …

The roles of androgens in male reproductive development and function in zebrafish are
poorly understood. To investigate this topic, we employed CRISPR/Cas9 to generate …

Sex determination is the process deciding the sex of a developing embryo. This is usually
determined genetically; however it is a delicate process, which in many cases can be …

The regulatory mechanism of gonadal sex differentiation, which is complex and regulated by
multiple factors, remains poorly understood in teleosts. Recently, we have shown that …

The spatial and temporal expression of steroidogenic genes in zebrafish has not been fully
characterised. Because zebrafish are increasingly employed in endocrine and stress …

Sex determination and differentiation are complex processes controlled by many different
factors; however, the relationships among these factors are poorly understood. Zebrafish …

Thyroid hormones are crucial mediators of many aspects of vertebrate life, including
reproduction. The key player is the biologically active 3, 5, 3'-triiodothyronine (T 3), whose …

Sex determinations are diverse in vertebrates. Although many sex-determining genes and
pathways are conserved, the mechanistic roles of these genes and pathways in the genetic …

In vertebrates, thyroid hormones are critical players in controlling different physiological
processes such as development, growth, metabolism among others. There is evidence in …