Epicardial adipose tissue may mediate deleterious effects of obesity and inflammation on the myocardium

M Packer - Journal of the American College of Cardiology, 2018 - jacc.org
Epicardial adipose tissue has unique properties that distinguish it from other depots of
visceral fat. Rather than having distinct boundaries, the epicardium shares an unobstructed …

[PDF][PDF] The role of epicardial adipose tissue in heart disease

Z Matloch, T Kotulák, M Haluzík - Physiological research, 2016 - biomed.cas.cz
Recent studies focused on epicardial fat, formerly relatively neglected component of the
heart, have elucidated some of its key roles. It possesses several properties that can …

Epicardial fat: physiological, pathological, and therapeutic implications

J Salazar, E Luzardo, JC Mejías, J Rojas… - Cardiology research …, 2016 - Wiley Online Library
Epicardial fat is closely related to blood supply vessels, both anatomically and functionally,
which is why any change in this adipose tissue's behavior is considered a potential risk …

Epicardial adipose tissue feeding and overfeeding the heart

G Iacobellis, G Barbaro - Nutrition, 2019 - Elsevier
Epicardial adipose tissue is a particular visceral fat depot with unique anatomic,
biomolecular, and genetic features. Epicardial fat displays both physiological and …

Epicardial adipose tissue: anatomic, biomolecular and clinical relationships with the heart

G Iacobellis, D Corradi, AM Sharma - Nature clinical practice …, 2005 - nature.com
A growing amount of evidence suggests that regional fat distribution plays an important part
in the development of an unfavorable metabolic and cardiovascular risk profile. Epicardial …

[HTML][HTML] Epicardial fat in the maintenance of cardiovascular health

Y Wu, A Zhang, DJ Hamilton, T Deng - Methodist DeBakey …, 2017 - ncbi.nlm.nih.gov
Epicardial fat is a unique adipose tissue located between the myocardium and the visceral
layer of pericardium. This tissue is characterized by highly active fatty acid metabolism and …

The double role of epicardial adipose tissue as pro-and anti-inflammatory organ

G Iacobellis, G Barbaro - Hormone and metabolic research, 2008 - thieme-connect.com
Obesity is associated with low grade inflammation. Whether this is just an adaptive response
to excess adiposity to maintain a normal oxygen supply or a chronic activation of the innate …

Human epicardial adipose tissue is a source of inflammatory mediators

T Mazurek, LF Zhang, A Zalewski, JD Mannion… - Circulation, 2003 - Am Heart Assoc
Background—Inflammatory mediators that originate in vascular and extravascular tissues
promote coronary lesion formation. Adipose tissue may function as an endocrine organ that …

Human epicardial fat: what is new and what is missing?

HS Sacks, JN Fain - Clinical and Experimental Pharmacology …, 2011 - Wiley Online Library
Putative physiological functions of human epicardial adipose tissue (EAT) include:(i) lipid
storage for the energy needs of the myocardium;(ii) thermoregulation, whereby brown fat …

Epicardial adipose tissue and cardiovascular disease

TH Le Jemtel, R Samson, K Ayinapudi, T Singh… - Current hypertension …, 2019 - Springer
Abstract Purpose of Review Epicardial adipose tissue has been associated with the
development/progression of cardiovascular disease. We appraise the strength of the …