[HTML][HTML] Engineered mesenchymal stem cell-derived extracellular vesicles: a state-of-the-art multifunctional weapon against Alzheimer's disease
T Yin, Y Liu, W Ji, J Zhuang, X Chen, B Gong, J Chu… - Theranostics, 2023 - ncbi.nlm.nih.gov
With the increase of population aging, the number of Alzheimer's disease (AD) patients is
also increasing. According to current estimates, approximately 11% of people over 65 suffer …
also increasing. According to current estimates, approximately 11% of people over 65 suffer …
Mesenchymal stem cell-derived extracellular vesicles: a glimmer of hope in treating Alzheimer's disease
LC Liew, T Katsuda, L Gailhouste… - International …, 2017 - academic.oup.com
One of the pathological hallmarks of Alzheimer's disease (AD) is the presence of
extracellular plaques resulting from the accumulation of beta-amyloid peptide (Aβ). To date …
extracellular plaques resulting from the accumulation of beta-amyloid peptide (Aβ). To date …
[HTML][HTML] Mesenchymal stem cell-derived extracellular vesicles ameliorate Alzheimer's disease-like phenotypes in a preclinical mouse model
Alzheimer's disease (AD) is an irreversible neurodegenerative disorder that affects more
than 44 million people worldwide. Despite the high disease burden, there is no effective …
than 44 million people worldwide. Despite the high disease burden, there is no effective …
[HTML][HTML] Mesenchymal stem cell-derived extracellular vesicles: An emerging diagnostic and therapeutic biomolecules for neurodegenerative disabilities
Mesenchymal stem cells (MSCs) are a type of versatile adult stem cells present in various
organs. These cells give rise to extracellular vesicles (EVs) containing a diverse array of …
organs. These cells give rise to extracellular vesicles (EVs) containing a diverse array of …
[HTML][HTML] New strategies of neurodegenerative disease treatment with extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs)
CP Palanisamy, JJ Pei, P Alugoju, NVA Anthikapalli… - Theranostics, 2023 - ncbi.nlm.nih.gov
Neurodegenerative diseases are characterized by the progressive loss of neurons and
intricate interactions between different cell types within the affected regions. Reliable …
intricate interactions between different cell types within the affected regions. Reliable …
Therapeutic efficacy and promise of stem cell-derived extracellular vesicles in Alzheimer's disease and other aging-related disorders
The term extracellular vesicles (EVs) refers to a variety of heterogeneous nanovesicles
secreted by almost all cell types, primarily for intercellular communication and maintaining …
secreted by almost all cell types, primarily for intercellular communication and maintaining …
Extracellular vesicles from mesenchymal stem cells exert pleiotropic effects on amyloid‐β, inflammation, and regeneration: a spark of hope for Alzheimer's disease …
CA Elia, M Losurdo, ML Malosio, S Coco - Bioessays, 2019 - Wiley Online Library
No cure yet exists for devastating Alzheimer's disease (AD), despite many years and
humongous efforts to find efficacious pharmacological treatments. So far, neither designing …
humongous efforts to find efficacious pharmacological treatments. So far, neither designing …
[HTML][HTML] Mesenchymal stem cell secretome and extracellular vesicles for neurodegenerative diseases: Risk-benefit profile and next steps for the market access
L Giovannelli, E Bari, C Jommi, F Tartara, D Armocida… - Bioactive Materials, 2023 - Elsevier
Neurodegenerative diseases represent a growing burden on healthcare systems worldwide.
Mesenchymal stem cells (MSCs) have shown promise as a potential therapy due to their …
Mesenchymal stem cells (MSCs) have shown promise as a potential therapy due to their …
[HTML][HTML] Mesenchymal stem cell-and extracellular vesicle-based therapies for Alzheimer's disease: progress, advantages, and challenges
RG de Jesus Gonçalves, JF Vasques… - Neural Regeneration …, 2023 - journals.lww.com
Alzheimer's disease is a severe, highly disabling neurodegenerative disease, clinically
characterized by a progressive decline in cognitive functions, and is the most common form …
characterized by a progressive decline in cognitive functions, and is the most common form …
Insights of extracellular vesicles of mesenchymal stem cells: a prospective cell-free regenerative medicine for neurodegenerative disorders
P Vatsa, R Negi, UA Ansari, VK Khanna… - Molecular …, 2022 - Springer
Mesenchymal stem cells (MSCs) are multipotent, adult stem cells which are found in
numerous tissues like the umbilical cord, Wharton's jelly, bone marrow, and adipose tissue …
numerous tissues like the umbilical cord, Wharton's jelly, bone marrow, and adipose tissue …
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