Rationale: With over seven million infections and $25 billion treatment cost, chronic ischemic
wounds are one of the most serious complications in the United States. The controlled …

Exosomes, as therapeutically relevant cell-secreted extracellular vesicles, have attracted
enormous interest because they participate in intercellular communication and facilitate …

Wound healing, especially of chronic wounds, is still an unmet therapeutic area since
assessment and management are extremely complicated. Although many efforts have been …

Chronic wounds including diabetic foot ulcers are clinical emergencies that need careful
management. Exosomes from human adipose-derived mesenchymal stem cells (hADSCs …

Chronic, subclinical inflammation was often observed in the diabetic wound area, causing
inadequate and delayed wound-healing effects by failing to initiate cell migration …

Chronic wounds have become an economic, social, and public health burden and need
advanced treatment. Platelet-rich plasma (PRP) has been used extensively in treatment of …

It remains a clinical challenge for cutaneous wound healing and skin regeneration.
Endothelial cells participate in the formation of blood vessels and play an important role in …

Diabetic ulcers represent a substantial societal and healthcare burden worldwide and
scarcely respond to current treatment strategies. This study was addressed to evaluate the …

Background Large area skin trauma has always been a great challenge for both patients
and clinicians. Exosomes originating from human adipose-derived mesenchymal stem cells …

Wound healing is known as one of the most complicated biological processes for injured
skin caused by surgical, trauma, burns, or diabetic diseases, which causes a nonfunctioning …