In this review we discuss the evidence that drug addiction, defined as a maladaptive
compulsive habit, results from the progressive subversion by addictive drugs of striatum …

This review discusses the evidence for the hypothesis that the development of drug
addiction can be understood in terms of interactions between Pavlovian and instrumental …

Drug addiction can be understood as a pathological subversion of normal brain learning
and memory processes strengthened by the motivational impact of drug-associated stimuli …

A decade ago, we hypothesized that drug addiction can be viewed as a transition from
voluntary, recreational drug use to compulsive drug-seeking habits, neurally underpinned by …

The reinforcing (rewarding) effects of psychomotor stimulants (cocaine and amphetamine)
depend on the mesocorticolimbic dopamine system innervating the nucleus accumbens …

Drug addiction is increasingly viewed as the endpoint of a series of transitions from initial
drug use—when a drug is voluntarily taken because it has reinforcing, often hedonic, effects …

The argument advanced in this review is that drug addiction can be understood in terms of
normal learning and memory systems of the brain which, through the actions of chronically …

Drug addiction may be associated with a loss of executive control over maladaptive
incentive habits. We hypothesize that these incentive habits result from a pathological …

Learning theory proposes that drug seeking is a synthesis of multiple controllers. Whereas
goal‐directed drug seeking is determined by the anticipated incentive value of the drug …

We revisit our hypothesis that drug addiction can be viewed as the endpoint of a series of
transitions from initial voluntarily drug use to habitual, and ultimately compulsive drug use …