Chemokines, which are basic proteins that exert their effects via G protein-coupled receptors
and a subset of the cytokine family, are mediators deeply involved in leukocyte migration …

Chemokines are a small family of cytokines that were first discovered as chemotactic factors
in leukocytes during inflammation, and reports on the relationship between chemokines and …

Abstract Chemokine (CC motif) ligand 7 (CCL7), a CC chemokine, is a chemotactic factor
and attractant for various kinds of leukocytes, including monocytes and neutrophils. CCL7 is …

Cancer is currently one of the leading causes of death worldwide and is one of the most
challenging major public health problems. The main challenges faced by clinicians in the …

A neoplastic tumor consists of cancer cells that interact with each other and non-cancerous
cells that support the development of the cancer. One such cell are tumor-associated …

Cancer is considered a life-threatening disease, and several factors are involved in its
development. Chemokines are small proteins that physiologically exert pivotal roles in …

CCL20, as a chemokine, plays an important role in rheumatoid arthritis, psoriasis, and other
diseases by binding to its receptor CCR6. Recent 10 years' research has demonstrated that …

Chemokine and the chemokine receptor have a key role in the tumor progress. Here, we
supposed that CCR 7 might induce the invasion, migration, and epithelial–mesenchymal …

The chemokine ligand CCL2 and its receptor CCR2 are implicated in the initiation and
progression of various cancers. CCL2 can activate tumour cell growth and proliferation …

Tumor-associated macrophages (TAMs) contribute to the progression and mortality of
various malignancies. We reported that high numbers of infiltrating TAMs were significantly …