Biological aging is characterized by irreversible cell cycle blockade, a decreased capacity
for tissue regeneration, and an increased risk of age-related diseases and mortality. A …

Aging is associated with a wide range of human disorders, including cancer, diabetes,
cardiovascular, and neurodegenerative diseases. Long thought to be an inexorable road …

Aging is an inevitable outcome of life, characterized by a progressive decline in tissue and
organ function. At a molecular level, it is marked by the gradual alterations of biomolecules …

Aging is the largest risk factor for many diseases, and the aging population is one of the
fastest growing in the Western world. Therefore it has become ever more important to …

Aging is a complex phenomenon, where damage accumulation, increasing deregulation of
biological pathways, and loss of cellular homeostasis lead to the decline of organismal …

The aging process has been one of the most necessary research fields in the current
century, and knowing different theories of aging and the role of different genetic, epigenetic …

During aging, the mechanisms that normally maintain health and stress resistance strikingly
decline, resulting in decrepitude, frailty, and ultimately death. Exactly when and how this …

Aging represents the multifactorial decline in physiological function of every living organism.
Over the past decades, several hallmarks of aging have been defined, including epigenetic …

Organismal aging and longevity are influenced by many complex interacting factors.
Epigenetics has recently emerged as another possible determinant of aging. Here, we …

As life expectancy increases worldwide, ageing and age-related diseases arise as a major
issue for societies around the globe. Understanding the biological mechanisms underlying …