Background: Cerebral ischemia is caused due to insufficient blood flow to brain cells. This
study evaluates the therapeutic effects of propionic acid (PA) on the abnormalities induced …

Objectives Cerebral ischemia-reperfusion leads to brain tissue injury. Inflammation and
apoptosis play pivotal roles in the pathology. α-Pinene is an organic compound of many …

Backgrounds Cerebral ischemia-reperfusion leads to brain tissue injury. Inflammation and
apoptosis play pivotal roles in the pathology. Objective α-Pinene is an organic compound of …

The pathophysiological mechanisms leading to neuronal injury in middle cerebral artery
occlusion (MCAO) model of cerebral stroke are complex and multifactorial that form the …

Perillyl alcohol (PA) is a monoterpene found in essential oils of mints, cherries, citreous fruits
and lemon grass, reported to have antioxidant and anti-inflammatory properties. However …

Perillaldehyde (PAH), one of the major oil components in Perilla frutescens, has anti-
inflammatory effects. Few studies have examined the neuroprotective effect of PAH on …

Multiple pathomechanisms of cerebral ischemia reperfusion (I/R) injuries can be
ameliorated by certain high-potential pharmaceutical substances. In the present study, we …

Increased production of reactive oxygen and nitrogen species following cerebral ischemia–
reperfusion is a major cause for neuronal injury. In hypercholesterolemic apolipoprotein E …

Purpose of research Since, transient focal cerebral ischaemia exhibits detrimental effect not
only during the course of ischaemia but also after the onset of reperfusion, the current study …

Some studies of animal models of middle cerebral artery occlusion indicate that
inflammation plays a key role in the pathogenesis of cerebral ischemia and secondary …