The adaptor protein CARD9 links detection of fungi by surface receptors to the activation of
the NF-κB pathway. Mice deficient in CARD9 exhibit dysbiosis and are more susceptible to …

Background & Aims Caspase recruitment domain 9 (CARD9) is an adaptor protein that
integrates signals downstream of pattern recognition receptors. CARD9 has been …

CARD9 is a signaling adaptor protein that is involved in the transduction of signals from a
variety of innate pattern recognition receptors, including the C-type lectin receptors and …

CARD9 is a central component of anti-fungal innate immune signaling via C-type lectin
receptors, and several immune-related disorders are associated with CARD9 alterations …

CARD9 is a caspase recruitment domain-containing signaling protein that plays a critical
role in innate and adaptive immunity. It has been widely demonstrated that CARD9 adaptor …

Inflammatory bowel diseases (IBD) are key risk factors for the development of colorectal
cancer, but the mechanisms that link intestinal inflammation with carcinogenesis are …

The caspase-recruitment domain–containing adaptor protein CARD9 regulates the innate
signaling responses to fungal infection. Here we show that CARD9 is required for innate …

The C-type lectin receptor–Syk (spleen tyrosine kinase) adaptor CARD9 facilitates protective
antifungal immunity within the central nervous system (CNS), as human deficiency in …

Caspase recruitment domain-containing protein (Card) 9 is a nonredundant adapter protein
that functions in the innate immune system in the assembly of multifunctional signaling …

CARD9 is a caspase recruitment domain‐containing signaling protein that is highly
expressed in dendritic cells and in macrophages. Work over the last two years has identified …