Reverse cholesterol transport and cholesterol efflux in atherosclerosis

R Ohashi, H Mu, X Wang, Q Yao, C Chen - Qjm, 2005 - academic.oup.com
Reverse cholesterol transport (RCT) is a pathway by which accumulated cholesterol is
transported from the vessel wall to the liver for excretion, thus preventing atherosclerosis …

The role of reverse cholesterol transport in animals and humans and relationship to atherosclerosis

DJ Rader, ET Alexander, GL Weibel, J Billheimer… - Journal of lipid …, 2009 - ASBMB
Reverse cholesterol transport (RCT) is a term used to describe the efflux of excess cellular
cholesterol from peripheral tissues and its return to the liver for excretion in the bile and …

Reverse cholesterol transport revisited: contribution of biliary versus intestinal cholesterol excretion

G Brufau, AK Groen, F Kuipers - Arteriosclerosis, thrombosis, and …, 2011 - Am Heart Assoc
Reverse cholesterol transport (RCT) is usually defined as high-density lipoprotein-mediated
transport of excess cholesterol from peripheral tissues, including cholesterol-laden …

[HTML][HTML] Increased ABCA1 activity protects against atherosclerosis

C Fievet, G Castro, ER James… - The Journal of …, 2002 - Am Soc Clin Investig
The ABC transporter ABCA1 plays a key role in the first steps of the reverse cholesterol
transport pathway by mediating lipid efflux from macrophages. Previously, it was …

Reverse cholesterol transport—a review of the process and its clinical implications

SA Hill, MJ McQueen - Clinical biochemistry, 1997 - Elsevier
Objectives: This review article will summarize the current knowledge surrounding the
reverse cholesterol transport system; the process, the effect of mutations in genes coding for …

An overview of reverse cholesterol transport.

AR Tall - European heart journal, 1998 - europepmc.org
Reverse cholesterol transport is a multi-step process resulting in the net movement of
cholesterol from peripheral tissues back to the liver via the plasma compartment. Cellular …

High density lipoproteins and arteriosclerosis: role of cholesterol efflux and reverse cholesterol transport

A Von Eckardstein, JR Nofer… - … , thrombosis, and vascular …, 2001 - Am Heart Assoc
High density lipoprotein (HDL) cholesterol is an important risk factor for coronary heart
disease, and HDL exerts various potentially antiatherogenic properties, including the …

Different pathways of cellular cholesterol efflux

AD Dergunov, VB Baserova - Cell Biochemistry and Biophysics, 2022 - Springer
Cholesterol efflux is the first and rate-limiting step of reverse cholesterol transport (RCT) from
peripheric cells to the liver. The involvement of high-density lipoprotein (HDL) in RCT …

Molecular regulation of macrophage reverse cholesterol transport

X Wang, DJ Rader - Current opinion in cardiology, 2007 - journals.lww.com
Increasing evidence has suggested that ATP-binding cassette transporter A1 and ATP-
binding cassette transporter G1 are involved in macrophage reverse cholesterol transport. In …

HDL and reverse remnant-cholesterol transport (RRT): relevance to cardiovascular disease

A Kontush - Trends in molecular medicine, 2020 - cell.com
Cardiovascular diseases predominantly result from atherosclerosis, a natural biological
phenomenon reflecting food intake and energy production in humans. Lipolysis of plasma …