[HTML][HTML] Capsaicin: A two-decade systematic review of global research output and recent advances against human cancer

TL Adetunji, F Olawale, C Olisah, AE Adetunji… - Frontiers in …, 2022 - frontiersin.org
Capsaicin (8-methyl-N-vanillyl-6-nonenamide) is one of the most important natural products
in the genus Capsicum. Due to its numerous biological effects, there has been extensive …

Application of capsaicin as a potential new therapeutic drug in human cancers

S Zhang, D Wang, J Huang, Y Hu… - Journal of clinical …, 2020 - Wiley Online Library
What is known and objective Capsaicin, the major active ingredient of chili pepper, may play
a “dual role” in tumourigenesis, acting as a carcinogen or as a cancer preventive agent. The …

Anticancer properties of capsaicin against human cancer

R Clark, SH Lee - Anticancer research, 2016 - ar.iiarjournals.org
There is persuasive epidemiological and experimental evidence that dietary phytochemicals
have anticancer activity. Capsaicin is a bioactive phytochemical abundant in red and chili …

Capsaicin: A chili pepper bioactive phytocompound with a potential role in suppressing cancer development and progression

A Mondal, S Banerjee, W Terang… - Phytotherapy …, 2024 - Wiley Online Library
Cancer profoundly influences morbidity and fatality rates worldwide. Patients often have
dismal prognoses despite recent improvements in cancer therapy regimens. However …

An updated review on molecular mechanisms underlying the anticancer effects of capsaicin

SC Cho, H Lee, BY Choi - Food science and biotechnology, 2017 - Springer
The quest for developing anticancer principles from natural sources has a long historical
track record and remarkable success stories. The pungent principle of hot chili pepper …

[HTML][HTML] The effects of capsaicin on gastrointestinal cancers

GDA Popescu, C Scheau, IA Badarau, MD Dumitrache… - Molecules, 2020 - mdpi.com
Gastrointestinal (GI) cancers are a group of diseases with very high positions in the ranking
of cancer incidence and mortality. While they show common features regarding the …

[HTML][HTML] Capsaicin: a novel chemopreventive molecule and its underlying molecular mechanisms of action

AA Oyagbemi, AB Saba, OI Azeez - Indian journal of cancer, 2010 - journals.lww.com
Abstract Capsaicin (trans-8-methyl-N-vanillyl-6-nonenamide) is the a principal pungent
ingredient of hot red and chili peppers that belong to the plant genus Capsicum …

Anticancer activity of natural and synthetic capsaicin analogs

JR Friedman, NA Nolan, KC Brown, SL Miles… - … of Pharmacology and …, 2018 - ASPET
The nutritional compound capsaicin is the major spicy ingredient of chili peppers. Although
traditionally associated with analgesic activity, recent studies have shown that capsaicin has …

[HTML][HTML] Capsaicinoids: Multiple effects on angiogenesis, invasion and metastasis in human cancers

JR Friedman, SD Richbart, JC Merritt, KC Brown… - Biomedicine & …, 2019 - Elsevier
Cancer progression is a complex multistep process comprising of angiogenesis of the
primary tumor, its invasion into the surrounding stroma and its migration to distant organs to …

Anti-cancer activity of sustained release capsaicin formulations

JC Merritt, SD Richbart, EG Moles, AJ Cox… - Pharmacology & …, 2022 - Elsevier
Abstract Capsaicin (trans-8-methyl-N-vanillyl-6-noneamide) is a hydrophobic, lipophilic
vanilloid phytochemical abundantly found in chili peppers and pepper extracts. Several …