The culturing of cells in the laboratory under controlled conditions has always been crucial
for the advancement of scientific research. Cell-based assays have played an important role …

Although historically, the traditional bidimensional in vitro cell system has been widely used
in research, providing much fundamental information regarding cellular functions and …

3D cell-culture models have recently garnered great attention because they often promote
levels of cell differentiation and tissue organization not possible in conventional 2D culture …

Recently, research is undergoing a drastic change in the application of the animal model as
a unique investigation strategy, considering an alternative approach for the development of …

Cell culture is an important tool for biological research. Two-dimensional cell culture has
been used for some time now, but growing cells in flat layers on plastic surfaces does not …

Current fundamental investigations of human biology and the development of therapeutic
drugs commonly rely on 2D monolayer cell culture systems. However, 2D cell culture …

Drug discovery programmes require accurate in vitro systems for drug screening and testing.
Traditional cell culture makes use of 2D (two-dimensional) surfaces for ex vivo cell growth. In …

Cell culture systems are essential tools used in a wide range of biomedical and clinical
studies. Two dimensional cell culture models (2D) provide basic information on cytotoxicity …

The field of 3D cell culture and its applications is rooted in the understanding of cell biology,
tissue engineering, tissue morphology, disease mechanisms, and drug action. For many …

Despite tremendous advancements in technologies and resources, drug discovery still
remains a tedious and expensive process. Though most cells are cultured using 2D …