To characterize apoptosis in keloids and the mechanisms responsible for this process, the
expression of activated caspase‐9 and‐3 in fibroblasts obtained from keloids was analyzed …

Keloids are the result of a dysregulated wound‐healing process and are characterized by
formation of excess scar tissue that proliferates beyond the boundaries of the inciting wound …

Recent studies have suggested that the regulation of apoptosis during wound healing is
important in scar establishment and the development of pathological scarring. In this study …

Recent studies have suggested that the regulation of apoptosis during wound healing is
important in scar establishment and development of pathological scarring. To examine the …

Background. Physiologically programmed cell death or apoptosis occurs during the natural
balance between cellular proliferation and demise. Materials and Methods. We compared …

The purpose of this study was to determine if aberrant apoptosis plays a role in pathologic
wound healing as manifested by hypertrophic scarring and keloid formation. Apoptosis has …

Keloids are benign skin tumors and are the effect of a dysregulated wound-healing process
in genetically predisposed patients. They are characterized by formation of excess scar …

Apoptosis is a process of programmed cell death that occurs in multicellular organisms. The
mitochondrial pathway plays a paramount role in apoptosis. In this study, the expression …

There is no established pharmacological therapy for skin keloids, a wound healing disorder.
In this study, we investigated the effect of N-benzoyl staurosporine (PKC412), a protein …

Excessive scar formation in keloids points to altered tissue modeling and repair
mechanisms. Dysregulation of cytokine and apoptotic cascades and their downstream …