Basic fibroblast growth factor attenuates bisphosphonate-induced oxidative injury but decreases zinc and copper levels in oral epithelium of rat

G Koçer, M Nazıroğlu, Ö Çelik, L Önal… - Biological trace element …, 2013 - Springer
Recent studies have reported oxidative damage due to bisphosphonate (BP) in various
cancer tissues and neurons, although basic fibroblast growth factor (bFGF) induced …

Effects of bisphosphonate on oxidative stress levels in patients with different types of cancer

M Koçer, M Nazıroğlu, G Koçer, TT Sönmez - Cancer Investigation, 2014 - Taylor & Francis
We investigated the effects of bisphosphonate (BP) on oxidative stress levels in blood of
patients with cancer. In total, 19 patients with cancer and 21 healthy subjects were included …

[HTML][HTML] Osteonecrosis of the jaws caused by bisphosphonate treatment and oxidative stress in mice

J Tamaoka, K Takaoka, H Hattori… - Experimental and …, 2019 - spandidos-publications.com
Aging is a significant risk factor for the development of bisphosphonate‑related
osteonecrosis of the jaws (BRONJ). Accumulating evidence suggests that bone aging is …

[HTML][HTML] Repercussions of bisphenol a on the physiology of human osteoblasts

E García-Recio, VJ Costela-Ruiz… - International journal of …, 2022 - mdpi.com
(1) Background: Bisphenol A (BPA) is an endocrine disruptor that is widely present in the
environment and exerts adverse effects on various body tissues. The objective of this study …

Bisphosphonate‐induced reactive oxygen species inhibit proliferation and migration of oral fibroblasts: A pathogenesis of bisphosphonate‐related osteonecrosis of …

N Taniguchi, M Osaki, K Onuma… - Journal of …, 2020 - Wiley Online Library
Background The onset mechanism for bisphosphonate‐related osteonecrosis of the jaw
(BRONJ) has been reported, with a focus on bone remodeling, biofilm formation, and …

[HTML][HTML] Prevention of tooth extraction-triggered bisphosphonate-related osteonecrosis of the jaws with basic fibroblast growth factor: An experimental study in rats

M Imada, T Yagyuu, Y Ueyama, M Maeda… - PLoS …, 2019 - journals.plos.org
Osteonecrosis of the jaw induced by administration of bisphosphonates (BPs), BP-related
osteonecrosis (BRONJ), typically develops after tooth extraction and is medically …

The cytotoxic effects of three different bisphosphonates in-vitro on human gingival fibroblasts, osteoblasts and osteogenic sarcoma cells

Y Açil, B Möller, P Niehoff, K Rachko, V Gassling… - Journal of Cranio …, 2012 - Elsevier
INTRODUCTION: Osteonecrosis of the jaw (ONJ) is an emerging condition in patients
undergoing long-term administration of bisphosphonates (BP) for the treatment of …

PDGF-BB exhibited therapeutic effects on rat model of bisphosphonate-related osteonecrosis of the jaw by enhancing angiogenesis and osteogenesis

S Gao, R Lin, S Huang, Y Liang, X Li, S Zhang… - Bone, 2021 - Elsevier
The mechanism and effective treatment of bisphosphonate-related osteonecrosis of the jaw
(BRONJ) are still uncertain. Our previous study revealed that zoledronate (ZOL) …

[HTML][HTML] Impact of bisphosphonates on the proliferation and gene expression of human fibroblasts

FJ Manzano-Moreno, R Illescas-Montes… - … Journal of Medical …, 2019 - ncbi.nlm.nih.gov
The aim of this study was to elucidate the role of fibroblasts in bisphosphonate-related
osteonecrosis of the jaw (BRONJ), evaluating the effect of zoledronate, alendronate, and …

Effects of glucocorticoid-induced osteoporosis on bone tissue of rats with experimental periodontitis

LHT Sousa, EV Moura, AL Queiroz, D Val… - Archives of Oral …, 2017 - Elsevier
Objective To evaluate the effects of osteoporosis induced by glucocorticoid (GIOP) on bone
tissue of rats with experimental periodontitis (EP). Design 48 male Wistar rats divided into …