Mitochondrial transplantation attenuates cerebral ischemia‐reperfusion injury: possible involvement of mitochondrial component separation

Q Xie, J Zeng, Y Zheng, T Li, J Ren… - Oxidative Medicine …, 2021 - Wiley Online Library
Background. Mitochondrial dysfunctions play a pivotal role in cerebral ischemia‐reperfusion
(I/R) injury. Although mitochondrial transplantation has been recently explored for the …

Neurons release injured mitochondria as “help-me” signaling after ischemic stroke

L Gao, F Liu, PP Hou, A Manaenko, ZP Xiao… - Frontiers in Aging …, 2022 - frontiersin.org
Mitochondrial dysfunction has been regarded as one of the major contributors of ischemic
neuronal death after stroke. Recently, intercellular mitochondrial transfer between different …

Mitochondria as a therapeutic target for ischemic stroke

Z He, N Ning, Q Zhou, SE Khoshnam… - Free Radical Biology and …, 2020 - Elsevier
Stroke is the leading cause of death and physical disability worldwide. Mitochondrial
dysfunction has been considered as one of the hallmarks of ischemic stroke and contributes …

Muscle-derived autologous mitochondrial transplantation: a novel strategy for treating cerebral ischemic injury

Z Zhang, Z Ma, C Yan, K Pu, M Wu, J Bai, Y Li… - Behavioural brain …, 2019 - Elsevier
The available evidence showed that mitochondrial transfer by releasing the extracellular
vesicles containing mitochondria from astrocytes to neurons exerted a neuroprotective effect …

Mitochondrial transplantation therapy for ischemia reperfusion injury: a systematic review of animal and human studies

K Hayashida, R Takegawa, M Shoaib, T Aoki… - Journal of Translational …, 2021 - Springer
Background Mitochondria are essential organelles that provide energy for cellular functions,
participate in cellular signaling and growth, and facilitate cell death. Based on their …

[HTML][HTML] Mitochondria in ischemic stroke: new insight and implications

F Liu, J Lu, A Manaenko, J Tang, Q Hu - Aging and disease, 2018 - ncbi.nlm.nih.gov
Stroke is the leading cause of death and adult disability worldwide. Mitochondrial
dysfunction has been regarded as one of the hallmarks of ischemia/reperfusion (I/R) …

New insights into targeting mitochondria in ischemic injury

J Jia, H Jin, D Nan, W Yu, Y Huang - Apoptosis, 2021 - Springer
Stroke is the leading cause of adult disability and death worldwide. Mitochondrial
dysfunction has been recognized as a marker of neuronal death during ischemic stroke …

Different roles of mitochondria in cell death and inflammation: Focusing on mitochondrial quality control in ischemic stroke and reperfusion

M Carinci, B Vezzani, S Patergnani, P Ludewig… - Biomedicines, 2021 - mdpi.com
Mitochondrial dysfunctions are among the main hallmarks of several brain diseases,
including ischemic stroke. An insufficient supply of oxygen and glucose in brain cells …

Mitochondrial transfer as a therapeutic strategy against ischemic stroke

W Chen, J Huang, Y Hu, SE Khoshnam… - Translational stroke …, 2020 - Springer
Stroke is a debilitating disease that remains the second leading cause of death and
disability worldwide. Despite accumulating knowledge of the disease pathology, treatments …

Transferring xenogenic mitochondria provides neural protection against ischemic stress in ischemic rat brains

PJ Huang, CC Kuo, HC Lee, CI Shen… - Cell …, 2016 - journals.sagepub.com
Transferring exogenous mitochondria has therapeutic effects on damaged heart, liver, and
lung tissues. Whether this protective effect requires the symbiosis of exogenous …