GH influences female fertility. The goal of the present study was to obtain more insight into
the effect of loss of GH signalling, as observed in humans suffering from Laron syndrome, on …

We previously demonstrated that the development of cultured rat pre-antral follicles is
stimulated by growth hormone (GH) and insulin-like growth factor-I (IGF-I) and that the …

Although the primary control of gonadotropin secretion is by the hypothalamic GnRH and the
gonadal function is controlled by the pituitary gonadotropins and prolactin, the emerging …

To analyze the consequences of the absence of GH receptor (GHR) and GH-binding protein
(GHBP) on female reproductive function, we used a mouse model in which the GHR/GHBP …

The aim of the present study was to investigate whether growth hormone (GH) has any effect
on the development of cultured rat pre-antral follicles. Pre-antral follicles with a diameter …

In contrast to the many detailed studies of Graafian follicles, the biology of small follicles in
the human ovary is poorly understood and the trigger for follicular growth initiation remains …

The stimulatory effects of gonadotropins on antral and preovulatory follicles are well known,
but conflicting results have been reported regarding the gonadotropin responsiveness and …

Ovarian primordial follicle reserve is considered hormonally independent or subject to
depletion by FSH-driven follicle recruitment. To explore specific in vivo effects of FSH on …

Several clinical studies have shown a correlation of hypersecretion of LH and polycystic
ovary syndrome (PCOS), infertility, and miscarriage in women, suggesting that chronically …

The aim of this study was to investigate whether GH and insulin-like growth factor I (IGF-I)
are involved in preantral folliculogenesis and, if so, to clarify the relationship between …