Since conventional human cardiac two-dimensional (2D) cell culture and multilayered three-
dimensional (3D) models fail in recapitulating cellular complexity and possess inferior …

This protocol describes 3D bioprinting of cardiac tissue without the use of biomaterials,
using only cells. Cardiomyocytes, endothelial cells and fibroblasts are first isolated, counted …

Engineered heart tissue (EHT) has ample potential as a model for in vitro tissue modeling or
tissue regeneration. Using 3D cell printing technology, various hydrogels have been utilized …

Bioengineering of a functional cardiac tissue composed of primary cardiomyocytes has great
potential for myocardial regeneration and in vitro tissue modeling. However, its applications …

Current in vivo and in vitro models fail to accurately recapitulate the human heart
microenvironment for biomedical applications. This study explores the use of cardiac …

Abstract Three-dimensional (3D) cardiac tissue bioprinting sits at the crossroads of
cardiovascular biology, additive manufacturing, and materials science and engineering. As …

Abstract Purpose of Review Bioengineering of functional cardiac tissue composed of
primary cardiomyocytes has great potential for myocardial regeneration and in vitro tissue …

Cardiovascular diseases such as myocardial infarction account for millions of worldwide
deaths annually. Cardiovascular tissues constitute a highly organized and complex three …

Abstract 3D bioprinting is a powerful technique for engineering tissues used to study cell
behavior and tissue properties in vitro. With the right formulation and printing parameters …

There has been tremendous interest in constructing in vitro cardiac tissue for a range of
fundamental studies of cardiac development and disease and as a commercial system to …