KTTKS is a matrikine that originates from the proteolytic hydrolysis of collagen. This peptide
stimulates ECM production and types I and III collagen expression in vitro. A more stable …

In this work, we report the synthesis of a peptide analogue of the KTTKS, termed Ac-Wahx-
KTTKS and evaluate its cytotoxicity and role in biosynthesis of collagen for future application …

To evaluate whether Palmitoyl-pentapeptide (Pal-KTTKS), a lipidated subfragment of type 1
pro-collagen (residues 212–216), plays a role in fibroblast contractility, the effect of Pal …

The synthesis and in vitro enzyme inhibition profile of a series of novel trifluoromethylketone
(TFMK) inhibitors of human plasma kallikrein (PK) are described. We have developed an …

With the aim of obtaining selective synthetic inhibitors of plasmin and plasma kallikrein, D-Ile—
Phe—Lys—CHZCI, Ile—Phe—Lys—CHZCI, D—Ile—Phe—Arg—CHZCI and lle—Phe—Arg …

In this paper the synthesis of the following elongated tuftsin analogs: Thr‐Lys‐Pro‐Lys‐Thr‐
Lys‐Pro‐Lys (I), Thr‐Lys‐Pro‐Lys‐Thr‐Lys‐Pro‐Arg (II) and Ala‐Lys‐Thr‐Lys‐Pro‐Arg‐Glu …

A parallel combinatorial library of over 1600 compounds has been designed and
synthesized for the development of new potential peptidomimetic protein tyrosine kinase …

The relative potencies of four main types of okadaic acid class compounds as inhibitors of
the catalytic subunits of protein serine/threonine phosphatases 1 and 2A and the protein …

Proteinase inhibitors are of high pharmaceutical interest and are drug candidates for a
variety of indications. Specific kallikrein inhibitors are important for their antitumor activity …

The four ketomethylene dipeptides Phe ψ (COCH2)(RS) Orn (6a) and Trp ψ (COCH2)(RS)
XX=(RS) Orn (6b),(RS) Arg (8b) and (RS) Lys (12b) have been aynthasized by a route …