Effects of Systemic Simvastatin on the Concentrations of Visfatin, Tumor Necrosis Factor‐α, and Interleukin‐6 in Gingival Crevicular Fluid in Patients with Type 2 …

MA Bahammam, MS Attia - Journal of immunology research, 2018 - Wiley Online Library
Purpose. The objective of this study is to explore the relationship between the levels of
interleukin‐(IL‐) 6, tumor necrosis factor‐(TNF‐) α, and visfatin and simvastatin usage, in the …

[HTML][HTML] The role of visfatin levels in gingival crevicular fluid as a potential biomarker in the relationship between obesity and periodontal disease

D Çetiner, A Uraz, S Öztoprak, G Akça - Journal of Applied Oral …, 2019 - SciELO Brasil
Objectives Visfatin is an adipokine that plays an important role in immune functions as a
growth factor, enzyme, and pro-inflammatory mediator. We aimed to determine the levels of …

[HTML][HTML] Interlinking periodontitis and type 2 diabetes mellitus by assessment of crevicular visfatin levels in health and in disease before and after initial periodontal …

V Mishra, L Shettar, M Bajaj, AS Math… - Journal of Clinical and …, 2016 - ncbi.nlm.nih.gov
Aim We aimed to estimate and compare the changes in the levels of visfatin in the Gingival
Crevicular Fluid (GCF) of healthy subjects and in subjects with periodontitis with or without …

Effect of topical simvastatin (1.2 mg) on gingival crevicular fluid interleukin-6, interleukin-8 and interleukin-10 levels in chronic periodontitis–A clinicobiochemical study

HS Grover, S Kapoor, A Singh - Journal of oral biology and craniofacial …, 2016 - Elsevier
Objectives The impact of simvastatin (SMV), a cholesterol lowering drug, on bone
metabolism appears to involve complex interaction with cholesterol metabolites, hormones …

Statins and IL-1β, IL-10, and MPO levels in gingival crevicular fluid: preliminary results

V Cicek Ari, YD Ilarslan, B Erman, B Sarkarati, I Tezcan… - Inflammation, 2016 - Springer
Statins possess a wide variety of pleiotropic properties that are independent of their lipid-
lowering abilities such as attenuating inflammation, oxidative stress, coagulation, platelet …

[HTML][HTML] Comparison of the inflammatory states of serum and gingival crevicular fluid in periodontitis patients with or without type 2 diabetes mellitus

XR Xu, JL Xu, L He, XE Wang, HY Lu… - Journal of Dental …, 2023 - Elsevier
Background/purpose: There is a two-way relationship between periodontitis and type 2
diabetes mellitus. This study aimed to compare the inflammatory states in serum and …

[HTML][HTML] Effects of statins on cytokines levels in gingival crevicular fluid and saliva and on clinical periodontal parameters of middle-aged and elderly patients with type …

H Zhang, Y Zhang, X Chen, J Li, Z Zhang, H Yu - Plos one, 2021 - journals.plos.org
Objective To analyze the effect of statins on cytokines levels in gingival crevicular fluid (GCF)
and saliva and on clinical periodontal parameters of middle-aged and elderly patients with …

Effect of non surgical periodontal therapy on gingival crevicular fluid and serum visfatin concentration in periodontal health and disease

NM Raghavendra, AR Pradeep, R Kathariya… - Disease …, 2012 - content.iospress.com
Visfatin is a pleiotropic mediator which acts as growth factor, cytokine, enzyme involved in
energy including nicotinamide adenine dinucleotide metabolism and has been recently …

Gingival crevicular fluid and serum visfatin concentration: their relationship in periodontal health and disease

AR Pradeep, NM Raghavendra… - Journal of …, 2011 - Wiley Online Library
Background: Visfatin is a pleiotropic mediator that acts as growth factor, cytokine, and
enzyme involved in energy including nicotinamide adenine dinucleotide metabolism and …

Increased visfatin expression is associated with nuclear factor-kappa B and phosphatidylinositol 3-kinase in periodontal inflammation

E Özcan, NI Saygun, R Ilıkçı, Y Karslıoğlu… - Clinical oral …, 2017 - Springer
Objective Visfatin is an adipocytokine that plays a role in regulating periodontal inflammation
by as yet identified mechanisms. It has been suggested that visfatin mediates inflammation …