Chemical synthesis is a well established route for producing many chemicals on a large
scale, but some drawbacks still exist in this process, such as unstable intermediates …

Sustainable production of chemicals from renewable non-food biomass has become a
promising alternative to overcome environmental issues caused by our heavy dependence …

Metabolic engineering efforts that harness living organisms to produce natural products and
other useful chemicals face inherent difficulties because the maintenance of life processes …

The combination of synthetic and systems biology is a powerful framework to study
fundamental questions in biology and produce chemicals of immediate practical application …

Production of chemicals in microorganisms is no longer restricted to products arising from
native metabolic potential. In this review, we highlight the evolution of metabolic engineering …

Plant metabolism represents an enormous repository of compounds that are of
pharmaceutical and biotechnological importance. Engineering plant metabolism into …

Through microbial engineering, biosynthesis has the potential to produce thousands of
chemicals used in everyday life. Metabolic engineering and synthetic biology are fields …

Speeding up design-build-test (DBT) cycles is a fundamental challenge facing biochemical
engineering. To address this challenge, we report a new cell-free protein synthesis driven …

Growing concerns over limited fossil resources and associated environmental problems are
motivating the development of sustainable processes for the production of chemicals, fuels …

Highlights•Microbial production of chemicals is an attractive alternative to chemical
synthesis.•An integrated approach would be required to construct robust microbial chemical …