Pancreatic cancer (PC) is a highly lethal tumor with controversial high glucose uptake and
hypomicrovascularity, and the hypomicrovasculature, which is considered to have poor …

Apical microvilli of polarized epithelial cells govern the absorption of metabolites and the
transport of fluid in tissues. Previously, we reported that tall and dense basal microvilli …

Pancreatic ductal adenocarcinoma (PDAC) is a nearly lethal neoplasm. It is a remarkably
stroma‐rich, vascular‐poor and hypo‐perfused tumour, which prevents efficient drug …

Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal neoplasm characterized by a
'fortress' of thick collagen fibres, abundant myofibroblasts, and paradoxically reduced …

Pancreatic cancer has a poor prognosis, and treatment strategies based on preclinical
research have not succeeded in significantly extending patient survival. This failure likely …

Abstract Background/Purpose The microvessel density (MVD) of most malignant tumors is
considered to be strongly related to metastasis and prognosis. Weidner's “hot spot method” …

Objectives Pancreatic cancer (PC) is one of the most aggressive malignancies due to the
high rate of metastasis. The mechanisms underlying metastasis need to be elucidated …

Background Nanomedicine offers an excellent opportunity to tackle treatment-refractory
malignancies by enhancing the delivery of therapeutics to the tumor site. High endothelial …

Background: Aerobic glycolysis is a hallmark of glucose metabolism in cancer. Previous
studies have suggested that cancer cell–derived extracellular vesicles (EVs) can modulate …

Circulating microvesicles are able to mediate long-distance cell–cell communications. It is
essential to understand how microvesicles from pancreatic cancer act on other cells in the …