Spermatogenesis is a complex and highly regulated process. The ability of spermatozoa to
perform its function depends on multiple physiological and genetic factors that are not fully …

It is hard to fathom that one of the most highly differentiated cells in the body, the
spermatozoon, spends over half of its developmental life without the capacity for nuclear …

Spermatozoa are unique cells that have highly compact DNA, motility (and hypermotility)
patterns, a specific morphology, localized mitochondria and an apical acrosome. They are …

Simple Summary Approximately 24% of men referred to assisted reproductive technology
(ART) present with idiopathic male infertility. The current standard analysis of human semen …

In mammals, sperm need to mature in the epididymis to gain fertilization competency.
However, the molecular mechanism underlying buffalo sperm maturation remains elusive …

Various types of PTMs play important roles in the regulation of sperm proteins. However,
most large‐scale proteomic studies only focused on a single type of modification due to the …

Spermatogenesis is the process by which terminally differentiated sperm are produced from
male germline stem cells. This complex developmental process requires the coordination of …

Understanding the cellular mechanisms that regulate mammalian sperm function is
strategically important for both the management of male infertility and the development of …

Testis, the only organ responsible for generating sperm, is by far the organ with the largest
variety of proteins and tissue-specific proteins in humans. In testis, spermatogenesis is a …

Introduction: The seminal proteome has been shown to directly influence the male fertile
potential. Post-translational modifications (PTMs) are significant changes that play a role in …