Identification of the cis-regulatory elements controlling cell-type specific gene expression
patterns is essential for understanding the origin of cellular diversity. Conventional assays to …

Single-cell ATAC-seq (scATAC-seq) profiles the chromatin accessibility landscape at single
cell level, thus revealing cell-to-cell variability in gene regulation. However, the high …

Mammalian tissues are composed of highly specialized cell types defined by distinct gene
expression patterns. Identification of cis-regulatory elements responsible for cell-type …

Background Recent innovations in single-cell Assay for Transposase Accessible Chromatin
using sequencing (scATAC-seq) enable profiling of the epigenetic landscape of thousands …

EpiScanpy is a toolkit for the analysis of single-cell epigenomic data, namely single-cell
DNA methylation and single-cell ATAC-seq data. To address the modality specific …

Characterizing epigenetic heterogeneity at the cellular level is a critical problem in the
modern genomics era. Assays such as single cell ATAC-seq (scATAC-seq) offer an …

The assay for transposase-accessible chromatin using sequencing (ATAC-seq) has become
the preferred method for mapping chromatin accessibility due to its time and input material …

Single-cell transcriptomics has transformed our ability to characterize cell states, but deep
biological understanding requires more than a taxonomic listing of clusters. As new methods …

ATAC-seq is a recently developed method to identify the areas of open chromatin in a cell.
These regions usually correspond to active regulatory elements and their location profile is …

Recent advances in single-cell technologies, including single-cell ATAC-seq (scATAC-seq),
have enabled large-scale profiling of the chromatin accessibility landscape at the single-cell …