UBC-Nepal Expedition: imposed oscillatory shear stress does not further attenuate flow-mediated dilation during acute and sustained hypoxia
JC Tremblay, CA Howe, PN Ainslie… - American Journal of …, 2018 - journals.physiology.org
Experimentally induced oscillatory shear stress (OSS) and hypoxia reduce endothelial
function in humans. Acute and sustained hypoxia may cause increases in resting OSS; …
function in humans. Acute and sustained hypoxia may cause increases in resting OSS; …
Oscillatory shear stress, flow-mediated dilatation, and circulating microparticles at sea level and high altitude
JC Tremblay, SR Thom, M Yang, PN Ainslie - Atherosclerosis, 2017 - Elsevier
Background and aims Exposing the endothelium to acute periods of imposed oscillatory
shear stress reduces endothelial function and elevates circulating microparticles (MPs) …
shear stress reduces endothelial function and elevates circulating microparticles (MPs) …
Endothelial function and shear stress in hypobaric hypoxia: time course and impact of plasma volume expansion in men
High-altitude exposure typically reduces endothelial function, and this is modulated by
hemoconcentration resulting from plasma volume contraction. However, the specific impact …
hemoconcentration resulting from plasma volume contraction. However, the specific impact …
Evidence of sex differences in the acute impact of oscillatory shear stress on endothelial function
JC Tremblay, TV Stimpson… - Journal of applied …, 2019 - journals.physiology.org
Acutely imposed oscillatory shear stress (OSS) reduces reactive hyperemia flow-mediated
dilation (RH-FMD) in conduit arteries of men; however, whether a similar impairment occurs …
dilation (RH-FMD) in conduit arteries of men; however, whether a similar impairment occurs …
UBC-Nepal expedition: upper and lower limb conduit artery shear stress and flow-mediated dilation on ascent to 5,050 m in lowlanders and Sherpa
JC Tremblay, RL Hoiland, HH Carter… - American Journal …, 2018 - journals.physiology.org
The study of conduit artery endothelial adaptation to hypoxia has been restricted to the
brachial artery, and comparisons with highlanders have been confounded by differences in …
brachial artery, and comparisons with highlanders have been confounded by differences in …
The effects of acute hypobaric hypoxia on arterial stiffness and endothelial function and its relationship to changes in pulmonary artery pressure and left ventricular …
CJ Boos, P Hodkinson, A Mellor, NP Green… - … altitude medicine & …, 2012 - liebertpub.com
Abstract Boos, Christopher J., Pete Hodkinson, Adrian Mellor, Nicholas P. Green, and David
R. Woods. High Alt. Med. Biol. 13: 105–111.—This study investigated, for the first time, the …
R. Woods. High Alt. Med. Biol. 13: 105–111.—This study investigated, for the first time, the …
Episodic bouts of hyperaemia and shear stress improve arterial blood flow and endothelial function
GJ Hodges, DG Stewart, PJ Davison… - European journal of …, 2018 - Springer
Introduction Exercise and heat stress lead to systemic improvements in arterial endothelial
function, vascular stiffness, and cardiopulmonary capacity. The improvements in endothelial …
function, vascular stiffness, and cardiopulmonary capacity. The improvements in endothelial …
Disturbed blood flow worsens endothelial dysfunction in moderate-severe chronic obstructive pulmonary disease
OF Barak, S Mladinov, RL Hoiland, JC Tremblay… - Scientific reports, 2017 - nature.com
The aims of this study were:(1) to test whether oscillatory shear stress further exacerbates
endothelial dysfunction in patients with moderate-severe COPD, and (2) to test whether low …
endothelial dysfunction in patients with moderate-severe COPD, and (2) to test whether low …
The impact of hypoxaemia on vascular function in lowlanders and high altitude indigenous populations
Exposure to hypoxia elicits widespread physiological responses that are critical for
successful acclimatization; however, these responses may induce apparent maladaptive …
successful acclimatization; however, these responses may induce apparent maladaptive …
UBC-Nepal Expedition: acute alterations in sympathetic nervous activity do not influence brachial artery endothelial function at sea level and high altitude
MM Tymko, JC Tremblay… - Journal of Applied …, 2017 - journals.physiology.org
Evidence indicates that increases in sympathetic nervous activity (SNA), and acclimatization
to high altitude (HA), may reduce endothelial function as assessed by brachial artery flow …
to high altitude (HA), may reduce endothelial function as assessed by brachial artery flow …
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