Materials and Methods The PLC filled with fibrin (n= 10) and fibrin gel loaded with 1-μg C3-
C2I and 2-μg C2II (n= 10) were compared to autologous nerve grafts (n= 10) in a 15-mm …

Introduction Aim of this study is to evaluate if regeneration in repair of nerve defects can be
improved by combination of a poly‐dl‐lactide‐ɛ‐caprolactone conduit (PLC) with long‐term …

Introduction: The aim of the presented study was to investigate nerve regeneration after
application of C3‐Toxin, a Rho‐GTPase inhibitor and to correlate morphometry …

The gold standard in surgical management of a peripheral nerve gap is currently autologous
nerve grafting. This confers patient morbidity and increases surgical time therefore …

Background: The use of biodegradable synthetic nerve conduits for the reconstruction of
segmental nerve defects has been extensively reported in both animal and human studies …

A new conduit made with a bioabsorbable copolymer, poly (l-lactide-co-6-caprolactone),
was evaluated in an animal model as a guide for nerve regeneration. The conduit had an …

Tensile stress and tensile strain directly affect the quality of nerve regeneration after bridging
nerve defects by poly (lactic-co-glycolic acid) conduit transplantation and autogenous nerve …

OBJECTIVE Peripheral nerve adhesion caused by extraneural and intraneural scar
formation after neurolysis leads to nerve dysfunction. The authors previously developed a …

Background: Restoring peripheral nerve function after long gap peripheral nerve damage is
challenging. Lithium chloride has demonstrated neuroprotective qualities and therefore …

A biodegradable copolymer of poly L-lactic acid and ε-caprolactone (PLAC) was
manufactured into a tube, in which a denatured skeletal muscle segment was placed …