Fusobacterium nucleatum aggravates ulcerative colitis through promoting gut microbiota dysbiosis and dysmetabolism

S Lin, X Zhang, X Zhu, J Jiao, Y Wu… - Journal of …, 2023 - Wiley Online Library
Background The correlation between periodontitis and ulcerative colitis (UC) has drawn
widespread attention recently. Fusobacterium nucleatum (F. nucleatum) as a periodontal …

Fusobacterium nucleatum exacerbates colitis by damaging epithelial barriers and inducing aberrant inflammation

H Liu, XL Hong, TT Sun, XW Huang… - Journal of Digestive …, 2020 - Wiley Online Library
Objective Fusobacterium nucleatum (F. nucleatum) has been reported to be enriched in
patients with inflammatory bowel disease (IBD). This study aimed to explore the role of F …

Effect of the Progression of Fusobacterium nucleatum–induced Apical Periodontitis on the Gut Microbiota

H Haraga, T Sato, K Watanabe, N Hamada… - Journal of …, 2022 - Elsevier
Introduction Fusobacterium nucleatum, which is involved in the development of periodontal
disease and apical lesions, can be transmitted to the colon and metastasize to colorectal …

Fusobacterium nucleatum Accelerates the Progression of Colitis-Associated Colorectal Cancer by Promoting EMT

MR Yu, HJ Kim, HR Park - Cancers, 2020 - mdpi.com
Simple Summary Colitis-associated cancer (CAC) are associated with the development and
progression of colorectal cancer (CRC). And Fusobacterium nucleatum (F. nucleatum), a …

Fusobacterium nucleatum Promotes the Development of Ulcerative Colitis by Inducing the Autophagic Cell Death of Intestinal Epithelial

W Su, Y Chen, P Cao, Y Chen, Y Guo… - Frontiers in cellular …, 2020 - frontiersin.org
There is a growing body of evidence which suggests that intestinal microbiota, especially
Fusobacterium nucleatum (F. nucleatum), are associated with intestinal immune disease …

Fusobacterium nucleatum facilitates ulcerative colitis through activating IL‐17F signaling to NF‐κB via the upregulation of CARD3 expression

Y Chen, Y Chen, P Cao, W Su, N Zhan… - The Journal of …, 2020 - Wiley Online Library
Accumulating evidence links Fusobacterium nucleatum with ulcerative colitis (UC). The
mechanism by which F. nucleatum promotes intestinal inflammation in UC remains poorly …

Fusobacterium nucleatum Facilitates Apoptosis, ROS Generation, and Inflammatory Cytokine Production by Activating AKT/MAPK and NF‐κB Signaling Pathways in …

W Kang, Z Jia, D Tang, Z Zhang, H Gao… - Oxidative medicine …, 2019 - Wiley Online Library
Fusobacterium nucleatum (F. nucleatum) plays key roles in the initiation and progression of
periodontitis. However, the pathogenic effect of F. nucleatum on human oral tissues and …

[HTML][HTML] Fusobacterium nucleatum promotes colon cancer progression by changing the mucosal microbiota and colon transcriptome in a mouse model

N Wu, YQ Feng, N Lyu, D Wang, WD Yu… - World journal of …, 2022 - ncbi.nlm.nih.gov
BACKGROUND Fusobacterium nucleatum (F. nucleatum) has long been known to cause
opportunistic infections and has recently been implicated in colorectal cancer (CRC), which …

[HTML][HTML] Oral infection of mice with Fusobacterium nucleatum results in macrophage recruitment to the dental pulp and bone resorption

L Johnson, CLC Almeida-da-Silva, CM Takiya… - biomedical …, 2018 - Elsevier
Background Fusobacterium nucleatum is a Gram-negative anaerobic bacterium associated
with periodontal disease. Some oral bacteria, like Porphyromonas gingivalis, evade the host …

The Pathogenic Effects of Fusobacterium nucleatum on the Proliferation, Osteogenic Differentiation, and Transcriptome of Osteoblasts

H Gao, T Sun, F Yang, J Yuan, M Yang… - Frontiers in Cell and …, 2020 - frontiersin.org
As one of the most common oral diseases, periodontitis is closely correlated with tooth loss
in middle-aged and elderly people. Fusobacterium nucleatum (F. nucleatum) contributes to …