Murine peritoneal macrophages in vitro could kill Aspergillus fumigatus conidia, and this
activity could be suppressed with dexamethasone. Treatment with granulocyte/macrophage …

Dexamethasone (DEX) is a potent immunosuppressive agent used in the treatment of
several disorders. However, despite its beneficial effects, DEX puts patients at risk for …

The objectives of this study were to:(i) see if granulocyte macrophage colony-stimulating
factor (GM-CSF) could protect bronchoalveolar macrophages (BAM) against suppression by …

The in vivo and ex vivo effects of macrophage colony-stimulating factor (M-CSF) were
studied in a profoundly neutropenic rabbit model in order to determine its potential to …

The effects of recombinant human macrophage colony-stimulating factor (M-CSF) on
antifungal activity of human monocytes (MNC), MNC-derived macro phages (MDM), and …

GM-CSF has eVects on the phagocytosis rate, protein and RNA synthesis, and antimicrobial
killing functions of macrophages [1]. When these actions are studied in cell systems …

Production of the proinflammatory cytokines interleukin (IL)–1α and tumor necrosis factor
(TNF)–α and of the chemotactic chemokine macrophage inflammatory protein (MIP)–1α by …

Background The dexamethasone (DEX) immunosuppressive effect on macrophage killing
activity and cytokine production in response to Aspergillus fumigatus conidia is antagonized …

Neutrophils (PMNs) are a critical line of defense against Aspergillus fumigatus infection.
Increased frequency of invasive aspergillosis has been observed in patients receiving …

There is substantial evidence that local production of proinflammatory cytokines are very
important in host resistance to aspergillosis. Dexamethasone (DEX) down-regulates …