Approximately 1.5 billion people worldwide are overweight or affected by obesity, and are at
risk of developing type 2 diabetes, cardiovascular disease and related metabolic and …

Obesity is an important component of the pathophysiology of chronic diseases. Identifying
epigenetic modifications associated with elevated adiposity, including DNA methylation …

Background: Adiposity is a risk factor for type 2 diabetes and cardiovascular disease,
suggesting an important role for adipose tissue in the development of these conditions. The …

Background Obesity is a major health problem that is determined by interactions between
lifestyle and environmental and genetic factors. Although associations between several …

Objective/methods DNA methylation plays an important role in obesity and related metabolic
complications. We examined genome-wide DNA promoter methylation along with mRNA …

Background: Recent technological advances in epigenome profiling have led to an
increasing number of studies investigating the role of the epigenome in obesity. There is …

Epigenomics regulates gene expression and is as important as genomics in precision
personal health, as it is heavily influenced by environment and lifestyle. We profiled whole …

Obesity is associated with increased risk of several diseases and has become epidemic.
Obesity is highly heritable but the genetic variants identified by genome-wide association …

Background DNA methylation has been shown to be associated with adiposity in adulthood.
However, whether similar DNA methylation patterns are associated with childhood and …

Epigenetic modifications such as DNA methylation play a key role in gene regulation and
disease susceptibility. However, little is known about the genome-wide frequency …