Human adipose-derived mesenchymal stem cells-derived exosomes encapsulated in pluronic F127 hydrogel promote wound healing and regeneration

Y Zhou, XL Zhang, ST Lu, NY Zhang, HJ Zhang… - Stem cell research & …, 2022 - Springer
Background Large area skin trauma has always been a great challenge for both patients
and clinicians. Exosomes originating from human adipose-derived mesenchymal stem cells …

Exosomes derived from human adipose mensenchymal stem cells accelerates cutaneous wound healing via optimizing the characteristics of fibroblasts

LI Hu, J Wang, X Zhou, Z Xiong, J Zhao, R Yu… - Scientific reports, 2016 - nature.com
Prolonged healing and scar formation are two major challenges in the treatment of soft
tissue trauma. Adipose mesenchymal stem cells (ASCs) play an important role in tissue …

Combined topical and systemic administration with human adipose-derived mesenchymal stem cells (hADSC) and hADSC-derived exosomes markedly promoted …

Y Zhou, B Zhao, XL Zhang, Y Lu, ST Lu… - Stem cell research & …, 2021 - Springer
Background Cutaneous wound healing and regeneration have become a recognized health
challenge in the world, which causes severe damage to the mental and physical health of …

Adipose tissue-derived mesenchymal stem cell-derived exosomes promote wound healing and tissue regeneration

JH Lee, YJ Won, H Kim, M Choi, E Lee… - International Journal of …, 2023 - mdpi.com
Wound healing is a complex process involving cell proliferation, migration, and extracellular
matrix (ECM) remodeling. Extracellular vesicles (EVs) or exosomes derived from adipose …

Human exosomes accelerate cutaneous wound healing by promoting collagen synthesis in a diabetic mouse model

B Zhao, X Zhang, Y Zhang, Y Lu, W Zhang… - Stem cells and …, 2021 - liebertpub.com
Chronic wounds including diabetic foot ulcers are clinical emergencies that need careful
management. Exosomes from human adipose-derived mesenchymal stem cells (hADSCs …

Adipose‐derived mesenchymal stem cell‐derived exosomes biopotentiated extracellular matrix hydrogels accelerate diabetic wound healing and skin regeneration

Y Song, Y You, X Xu, J Lu, X Huang, J Zhang… - Advanced …, 2023 - Wiley Online Library
Wound healing is an urgent clinical challenge, particularly in the case of chronic wounds.
Traditional approaches to wound healing have limited therapeutic efficacy due to lengthy …

Exosome loaded genipin crosslinked hydrogel facilitates full thickness cutaneous wound healing in rat animal model

Q Li, S Gong, W Yao, Z Yang, R Wang, Z Yu, M Wei - Drug Delivery, 2021 - Taylor & Francis
Full thickness cutaneous wound therapy and regeneration remains a critical challenge in
clinical therapeutics. Recent reports have suggested that mesenchymal stem cells …

[HTML][HTML] Mesenchymal stem cell-derived exosomes: A novel and potential remedy for cutaneous wound healing and regeneration

JC Hu, CX Zheng, BD Sui, WJ Liu… - World journal of stem cells, 2022 - ncbi.nlm.nih.gov
Poor healing of cutaneous wounds is a common medical problem in the field of
traumatology. Due to the intricate pathophysiological processes of wound healing, the use of …

Umbilical cord-derived mesenchymal stem cell-derived exosomes combined pluronic F127 hydrogel promote chronic diabetic wound healing and complete skin …

J Yang, Z Chen, D Pan, H Li, J Shen - International journal of …, 2020 - Taylor & Francis
Purpose Chronic refractory wounds are a multifactorial comorbidity of diabetes mellitus with
the characteristic of impaired vascular networks. Currently, there is a lack of effective …

Exosome-loaded hydrogels: a new cell-free therapeutic approach for skin regeneration

B Safari, M Aghazadeh, S Davaran… - European Journal of …, 2022 - Elsevier
The treatment of unhealable and chronic cutaneous wounds is a significant challenge for the
healthcare system. Hence, there has been heightened interest in the development of …