Oxidative stress caused by the production of reactive oxygen species (ROS) plays a major
role in inflammatory processes. We hypothesized that modulation of ROS via quercetin may …

Results The LPS treatment led to increased alveolar wall thickening and cellular infiltration
in the lung, which was markedly prevented by quercetin pretreatment. Moreover, quercetin …

Cigarette smoking causes persistent lung inflammation that is mainly regulated by redox‐
sensitive pathways. We have previously reported that cigarette smoke (CS) activates …

Quercetin is a flavonoid molecule ubiquitous in nature and functions as an anti-oxidant and
anti-inflammatory agent with little toxicity in vivo and in vitro. Dose-and time-dependent effect …

Oxidants and tumor necrosis factor-α (TNF-α) activate transcription factors such as nuclear
factor-κB (NF-κB), which is involved in the transcription of proinflammatory mediators …

Background Acute respiratory distress syndrome (ARDS) can result in a life-threatening form
of respiratory failure, and established, effective pharmacotherapies are therefore urgently …

Oxidative stress plays an important role in the pathogenesis of chronic obstructive
pulmonary disease (COPD). The activation of nuclear factor erythroid 2-related factor 2 …

Abundant natural flavonoids can induce nuclear factor-erythroid 2 related factor 2 (Nrf2)
and/or AMP-activated protein kinase (AMPK) activation, which play crucial roles in the …

Background. Nowadays, atmospheric pollutants, ultraviolet rays, and other factors cause the
imbalance of cell redox, resulting in skin oxidative damage. There is an interaction between …

Toll-like receptors (TLRs) have been shown to play a pivotal role in both innate and adaptive
immune responses. TLR family is the essential recognition and signaling component of …