Beneficial effects of betaine: a comprehensive review
MK Arumugam, MC Paal, TM Donohue Jr, M Ganesan… - Biology, 2021 - mdpi.com
Simple Summary A large number of studies report that medicinal herbs and many food
ingredients protect against the development of liver disease because they possess …
ingredients protect against the development of liver disease because they possess …
Preventive and therapeutic role of betaine in liver disease: A review on molecular mechanisms
C Wang, C Ma, L Gong, S Dai, Y Li - European journal of pharmacology, 2021 - Elsevier
Betaine is a kind of water-soluble quaternary amine-type alkaloid widely existing in food,
such as wheat germ, beet, spinach, shrimp and wolfberry. As an important methyl donor and …
such as wheat germ, beet, spinach, shrimp and wolfberry. As an important methyl donor and …
Betaine chemistry, roles, and potential use in liver disease
CR Day, SA Kempson - Biochimica et Biophysica Acta (BBA)-General …, 2016 - Elsevier
Background Betaine is the trimethyl derivative of glycine and is normally present in human
plasma due to dietary intake and endogenous synthesis in liver and kidney. Betaine is …
plasma due to dietary intake and endogenous synthesis in liver and kidney. Betaine is …
Betaine increases mitochondrial content and improves hepatic lipid metabolism
L Zhang, Y Qi, Z ALuo, S Liu, Z Zhang, L Zhou - Food & function, 2019 - pubs.rsc.org
The liver plays a critical role in lipid metabolism. Hepatic dysfunction is not only the direct
cause of fatty liver disease, but the main risk factor for obesity, diabetes, and other metabolic …
cause of fatty liver disease, but the main risk factor for obesity, diabetes, and other metabolic …
Betaine improved adipose tissue function in mice fed a high-fat diet: a mechanism for hepatoprotective effect of betaine in nonalcoholic fatty liver disease
Z Wang, T Yao, M Pini, Z Zhou… - American journal of …, 2010 - journals.physiology.org
Adipose tissue dysfunction, featured by insulin resistance and/or dysregulated adipokine
production, plays a central role not only in disease initiation but also in the progression to …
production, plays a central role not only in disease initiation but also in the progression to …
Betaine in inflammation: mechanistic aspects and applications
G Zhao, F He, C Wu, P Li, N Li, J Deng, G Zhu… - Frontiers in …, 2018 - frontiersin.org
Betaine is known as trimethylglycine and is widely distributed in animals, plants, and
microorganisms. Betaine is known to function physiologically as an important …
microorganisms. Betaine is known to function physiologically as an important …
Betaine supplementation enhances lipid metabolism and improves insulin resistance in mice fed a high-fat diet
Obesity is a major driver of metabolic diseases such as nonalcoholic fatty liver disease,
certain cancers, and insulin resistance. However, there are no effective drugs to treat …
certain cancers, and insulin resistance. However, there are no effective drugs to treat …
Betaine as a functional ingredient: metabolism, health-promoting attributes, food sources, applications and analysis methods
Betaine is a non-essential amino acid with proven functional properties and underutilized
potential. The most common dietary sources of betaine are beets, spinach, and whole …
potential. The most common dietary sources of betaine are beets, spinach, and whole …
[HTML][HTML] Betaine transport in kidney and liver: use of betaine in liver injury
SA Kempson, K Vovor-Dassu, C Day - Cellular Physiology and …, 2013 - karger.com
Betaine, also known as trimethylglycine, is an important human nutrient obtained from a
variety of foods and also can be synthesized from choline. Betaine is much more abundant …
variety of foods and also can be synthesized from choline. Betaine is much more abundant …
Betaine treatment attenuates chronic ethanol‐induced hepatic steatosis and alterations to the mitochondrial respiratory chain proteome
KK Kharbanda, SL Todero, AL King… - … journal of hepatology, 2012 - Wiley Online Library
Introduction. Mitochondrial damage and disruption in oxidative phosphorylation contributes
to the pathogenesis of alcoholic liver injury. Herein, we tested the hypothesis that the …
to the pathogenesis of alcoholic liver injury. Herein, we tested the hypothesis that the …