The AGE-RAGE axis and RAGE genetics in chronic obstructive pulmonary disease

A Sharma, S Kaur, M Sarkar, BC Sarin… - Clinical Reviews in …, 2021 - Springer
Chronic obstructive pulmonary disease (COPD) is a heterogeneous group of lung diseases
limiting the airflow due to narrowing of airways, chronic bronchitis and emphysema that …

The AGE-RAGE Axis and the Pathophysiology of Multimorbidity in COPD

NL Reynaert, LEGW Vanfleteren… - Journal of Clinical …, 2023 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is a disease of the airways and lungs due to
an enhanced inflammatory response, commonly caused by cigarette smoking. Patients with …

RAGE: a new frontier in chronic airways disease

MB Sukkar, MA Ullah, WJ Gan… - British journal of …, 2012 - Wiley Online Library
Asthma and chronic obstructive pulmonary disease (COPD) are heterogeneous
inflammatory disorders of the respiratory tract characterized by airflow obstruction. It is now …

All the “RAGE” in lung disease: The receptor for advanced glycation endproducts (RAGE) is a major mediator of pulmonary inflammatory responses

EA Oczypok, TN Perkins, TD Oury - Paediatric respiratory reviews, 2017 - Elsevier
The receptor for advanced glycation endproducts (RAGE) is a pro-inflammatory pattern
recognition receptor (PRR) that has been implicated in the pathogenesis of numerous …

AGER expression and alternative splicing in bronchial biopsies of smokers and never smokers

A Faiz, M van den Berge, CJ Vermeulen… - Respiratory …, 2019 - Springer
Cigarette smoking is one of the major risk factors for the development of chronic obstructive
pulmonary disease (COPD). Evidence is accumulating that Receptor for Advanced Glycation …

Knockout of RAGE ameliorates mainstream cigarette smoke-induced airway inflammation in mice

M Chen, T Wang, Y Shen, D Xu, X Li, J An… - International …, 2017 - Elsevier
Background The receptor for advanced glycation end products (RAGE), a multiligand
receptor, has been proved to be implicated in inflammatory responses in chronic obstructive …

Soluble receptor for advanced glycation end products in COPD: relationship with emphysema and chronic cor pulmonale: a case-control study

M Miniati, S Monti, G Basta, F Cocci, E Fornai… - Respiratory …, 2011 - Springer
Background The receptor for advanced glycation end products (RAGE) is a multiligand
signal transduction receptor that can initiate and perpetuate inflammation. Its soluble isoform …

[HTML][HTML] Advanced glycation end products and its receptor (RAGE) are increased in patients with COPD

L Wu, L Ma, LFB Nicholson, PN Black - Respiratory medicine, 2011 - Elsevier
Advanced Glycation End products (AGEs) are the products of nonenzymatic glycation and
oxidation of proteins and lipids. Formation of AGEs is increased in response to …

Implication of receptor for advanced glycation end product (RAGE) in pulmonary health and pathophysiology

TK Mukherjee, S Mukhopadhyay, JR Hoidal - Respiratory physiology & …, 2008 - Elsevier
Receptor for advanced glycation end products (RAGE) is a membrane bound receptor and
member of the immunoglobulin super family and is normally present in a highly abundant …

Association of polymorphisms of the receptor for advanced glycation end products gene with COPD in the Chinese population

Y Li, C Yang, G Ma, X Gu, M Chen, Y Chen… - DNA and Cell …, 2014 - liebertpub.com
The receptor for advanced glycation end products (RAGE) is a cell surface molecule of the
immunoglobulin superfamily that binds diverse endogenous ligands involved in the …