The role of dendritic cells in cancer and anti-tumor immunity

AE Marciscano, N Anandasabapathy - Seminars in immunology, 2021 - Elsevier
Dendritic cells (DC) are key sentinels of the host immune response with an important role in
linking innate and adaptive immunity and maintaining tolerance. There is increasing …

Dendritic cells as orchestrators of anticancer immunity and immunotherapy

I Heras-Murillo, I Adán-Barrientos, M Galán… - Nature Reviews …, 2024 - nature.com
Dendritic cells (DCs) are a heterogeneous group of antigen-presenting innate immune cells
that regulate adaptive immunity, including against cancer. Therefore, understanding the …

Dendritic cells in cancer immunology and immunotherapy

SK Wculek, FJ Cueto, AM Mujal, I Melero… - Nature Reviews …, 2020 - nature.com
Dendritic cells (DCs) are a diverse group of specialized antigen-presenting cells with key
roles in the initiation and regulation of innate and adaptive immune responses. As such …

Dendritic cells and their role in immunotherapy

A Gardner, Á de Mingo Pulido, B Ruffell - Frontiers in immunology, 2020 - frontiersin.org
Despite significant advances in the field of cancer immunotherapy, the majority of patients
still do not benefit from treatment and must rely on traditional therapies. Dendritic cells have …

Dendritic cells and cancer: from biology to therapeutic intervention

B Wylie, C Macri, JD Mintern, J Waithman - Cancers, 2019 - mdpi.com
Inducing effective anti-tumor immunity has become a major therapeutic strategy against
cancer. Dendritic cells (DC) are a heterogenous population of antigen presenting cells that …

Dendritic cells as shepherds of T cell immunity in cancer

MJ Pittet, M Di Pilato, C Garris, TR Mempel - Immunity, 2023 - cell.com
In cancer patients, dendritic cells (DCs) in tumor-draining lymph nodes can present antigens
to naive T cells in ways that break immunological tolerance. The clonally expanded progeny …

DCision-making in tumors governs T cell anti-tumor immunity

F Alfei, PC Ho, WL Lo - Oncogene, 2021 - nature.com
The exploitation of T cell-based immunotherapies and immune checkpoint blockade for
cancer treatment has dramatically shifted oncological treatment paradigms and broadened …

Dendritic cells and cancer immunity

A Gardner, B Ruffell - Trends in immunology, 2016 - cell.com
Dendritic cells (DCs) are central regulators of the adaptive immune response, and as such
are necessary for T-cell-mediated cancer immunity. In particular, antitumoral responses …

[HTML][HTML] Dendritic cells in the cancer microenvironment

Y Ma, GV Shurin, Z Peiyuan, MR Shurin - Journal of Cancer, 2013 - ncbi.nlm.nih.gov
The complexity of the tumor immunoenvironment is underscored by the emergence and
discovery of different subsets of immune effectors and regulatory cells. Tumor-induced …

The role of dendritic cells in cancer

YS Lee, KJ Radford - International review of cell and molecular biology, 2019 - Elsevier
Cancer immunotherapy harnesses the ability of the immune system to recognize and
eliminate cancer. The potent ability of dendritic cells (DCs) to initiate and regulate adaptive …