2.8 A 88: Willian et al. and/or a pharmaceutically-acceptable salt, hydrate, Solvate, 4.74 s.
160 A 5, 1988 Bennion et al. tautomer, optical isomer, E-isomer, Z-isomer, or combination …

The invention relates to a compound of Formula (I) and/or a pharmaceutically-acceptable
salt, hydrate, solvate, tautomer, optical isomer, E-isomer, Z-isomer, or combination thereof …

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Patents US8927580B2 - Thiosemicarbazone compounds and use in the treatment of cancer …

C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with
other rings, with one nitrogen atom as the only ring hetero atom and three or more double …

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US PATENT DOCUMENTS hydroxy, an optionally hydroxylated, optionally alkoxylated
6,147,094. A 11/2000 Towart et al. alkyl or aminoalkyl group; R is a hydrogen atom or an …

5,840,746 A 11/1998 Ducharme et al. 5,916,596 A 6, 1999 Desai et al. 6,013,836 A 1/2000
Hsu et al. 6,096,331 A 8, 2000 Desai et al. 6,172,108 B1 1/2001 Vega et al. 6,172,188 B1 …

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This invention relates to solid oral pharmaceutical formulations or (S)-methyl ((4 (4-(3-(5-
chtoro-2-fluoro-3-(methyl-sutfonamido) phenyl)-1-isopropyl-1H-pyrazol-4-yl) pyrimidin-2-yl) …