Use of rapid drug desensitization in delayed hypersensitivity reactions to chemotherapy and monoclonal antibodies

A Vega, MI Peña, I Torrado - Frontiers in Allergy, 2022 - frontiersin.org
Background: Rapid drug desensitization (RDD) allows first-line therapies in patients with
immediate drug hypersensitivity reactions (DHR) to chemotherapeutic drugs (ChD) and …

One-dilution rapid desensitization protocol to chemotherapeutic and biological agents: a five-year experience

A Sala-Cunill, GJ Molina-Molina, JT Verdesoto… - The Journal of Allergy …, 2021 - Elsevier
Background Rapid drug desensitization (RDD) becomes a crucial procedure to allow
treatment continuation in patients who suffer drug hypersensitivity reactions (DHRs) to …

Rapid desensitization in immediate hypersensitivity reaction to drugs

P Giavina-Bianchi, MV Aun, VR Galvão… - … Treatment Options in …, 2015 - Springer
Opinion Statement Adverse drug reactions have increased dramatically worldwide, often
preventing the use of first-line therapies. Not infrequently, many patients presenting with …

Safety, costs, and efficacy of rapid drug desensitizations to chemotherapy and monoclonal antibodies

D Sloane, U Govindarajulu, J Harrow-Mortelliti… - The Journal of Allergy …, 2016 - Elsevier
Background Rapid drug desensitization (RDD) is used to address hypersensitivity reactions
to chemotherapeutics and monoclonal antibodies, allowing patients to be treated with …

Breakthrough reactions during rapid drug desensitization: clinical outcome and risk factors

Y Kang, OY Kwon, H Jung, M Kang, J An… - Annals of Allergy …, 2019 - Elsevier
Abstract Background Severe hypersensitivity reactions (HSRs) interfere with the
administration of necessary drugs for patients; drug desensitization can be a good …

Hypersensitivity reactions to mAbs: 105 desensitizations in 23 patients, from evaluation to treatment

PJ Brennan, TR Bouza, FI Hsu, DE Sloane… - Journal of Allergy and …, 2009 - Elsevier
BACKGROUND: Rapid desensitization, a procedure for graded drug administration, allows
for the safe readministration of a medication after certain types of hypersensitivity reactions …

Rapid drug desensitization with biologics: a single-center experience with four biologics

S Bavbek, R Kendirlinan, P Çerçi, S Altıner… - … Archives of Allergy and …, 2017 - karger.com
Background: Rapid drug desensitization (RDD) induces a temporary tolerance to biologics
which induce hypersensitivity reactions (HSRs). Data are limited regarding the use of RDD …

Desensitization for drug hypersensitivity to chemotherapy and monoclonal antibodies

R Bonamichi-Santos, M Castells - Current Pharmaceutical …, 2016 - ingentaconnect.com
Chemotherapies drugs and monoclonal antibodies are key components of the treatment of
cancer patients and patients with chronic inflammatory conditions to provide increase in life …

Drug desensitization in the management of hypersensitivity reactions to monoclonal antibodies and chemotherapy

V Mezzano, P Giavina-Bianchi, M Picard, J Caiado… - BioDrugs, 2014 - Springer
Hypersensitivity reactions to monoclonal antibodies and chemotherapy, which may vary in
severity from mild to life-threatening, can lead to their discontinuation and replacement by …

Rapid drug desensitization with chemotherapeutics (platins, taxanes, and others): a single-center retrospective study

R Kendirlinan, R Gümüşburun, P Çerçi… - … Archives of Allergy and …, 2019 - karger.com
Background: Rapid drug desensitization (RDD) induces a temporary tolerance to
chemotherapeutics that induce hypersensitivity reactions (HSRs). Purpose: Our objective is …