In vivo recognition and clearance of red blood cells containing phosphatidylserine in their plasma membranes.

AJ Schroit, JW Madsen, Y Tanaka - Journal of Biological Chemistry, 1985 - ASBMB
We have previously investigated the interaction of macrophages with red blood cells (RBC)
displaying phosphatidylserine (PS) in their surface membranes after the transfer of the …

Insertion of fluorescent phosphatidylserine into the plasma membrane of red blood cells. Recognition by autologous macrophages.

Y Tanaka, AJ Schroit - Journal of Biological Chemistry, 1983 - Elsevier
The interaction of macrophages with red blood cells (RBC) displaying phosphatidylserine
(PS) in their surface membranes was investigated after the transfer of an exogenously …

Transbilayer movement of phosphatidylserine in erythrocytes: inhibition of transport and preferential labeling of a 31 000-dalton protein by sulfhydryl reactive reagents

J Connor, AJ Schroit - Biochemistry, 1988 - ACS Publications
Revised Manuscript Received November 18, 1987 abstract: A series of labeled thiolation
reagents were synthesized on the basis of the parent structure pyridyldithioethylamine …

[HTML][HTML] Exposure of phosphatidylserine in the outer leaflet of human red blood cells. Relationship to cell density, cell age, and clearance by mononuclear cells.

J Connor, CC Pak, AJ Schroit - Journal of Biological Chemistry, 1994 - Elsevier
Human red blood cells (RBC) were separated by density on self-forming Percoll gradients
into five distinct populations. The transbilayer movement and equilibrium distribution of 1 …

The recognition of red blood cells by macrophages: role of phosphatidylserine and possible implications of membrane phospholipid asymmetry

AJ Schroit, Y Tanaka, J Madsen, IJ Fidler - Biology of the Cell, 1984 - Wiley Online Library
The recognition of phosphatidylserine (PS) by macrophages was investigated using inside‐
out (IO) red blood cell (RBC) ghosts and RBC displaying PS in their surface membranes …

Studies on sickled erythrocytes provide evidence that the asymmetric distribution of phosphatidylserine in the red cell membrane is maintained by both ATP …

E Middelkoop, BH Lubin, EM Bevers… - … et Biophysica Acta (BBA …, 1988 - Elsevier
In order to study factors which are involved in maintenance of phosphatidylserine (PS)
asymmetry within the human red cell membrane, we measured the effect of ATP-depletion …

Regulation of phosphatidylserine exposure in red blood cells

DB Nguyen, L Wagner-Britz, S Maia, P Steffen… - Cellular physiology and …, 2011 - karger.com
The exposure of phosphatidylserine (PS) on the outer membrane leaflet of red blood cells
(RBCs) serves as a signal for eryptosis, a mechanism for the RBC clearance from blood …

Differentiation-dependent expression of phosphatidylserine in mammalian plasma membranes: quantitative assessment of outer-leaflet lipid by prothrombinase …

J Connor, C Bucana, IJ Fidler… - Proceedings of the …, 1989 - National Acad Sciences
Phosphatidylserine (PS) is asymmetrically distributed in mammalian cell membranes, being
preferentially localized in the inner leaflet. Some studies have suggested that a disturbance …

Increased adherence of sickled and phosphatidylserine-enriched human erythrocytes to cultured human peripheral blood monocytes.

RS Schwartz, Y Tanaka, IJ Fidler… - The Journal of …, 1985 - Am Soc Clin Investig
The precise mechanism by which sickle erythrocytes (RBC) are removed from the circulation
is controversial, although it is possible that enhanced recognition of these cells by circulating …

Transmembrane phospholipid distribution in blood cells: control mechanisms and pathophysiological significance.

EM Bevers, P Comfurius, DW Dekkers… - Biological …, 1998 - europepmc.org
This review deals with current concepts on the regulation and function of phospholipid
asymmetry in biological membranes. This ubiquitous phenomenon is characterized by a …