Peptide cargo administration: current state and applications

H Rohira, A Arora, P Kaur, A Chugh - Applied Microbiology and …, 2023 - Springer
Effective delivery of drug molecules to the target site is a challenging task. In the last decade,
several innovations in the drug delivery system (DDS) have tremendously improved the …

[HTML][HTML] Overcoming the cellular barriers and beyond: Recent progress on cell penetrating peptide modified nanomedicine in combating physiological and …

Y Liu, Z Zhao, M Li - Asian Journal of Pharmaceutical Sciences, 2022 - Elsevier
The complex physiological and pathological conditions form barriers against efficient drug
delivery. Cell penetrating peptides (CPPs), a class of short peptides which translocate drugs …

New generation of cell‐penetrating peptides: functionality and potential clinical application

S Reissmann, MP Filatova - Journal of peptide science, 2021 - Wiley Online Library
Cell‐penetrating peptides (CPPs) can transport various cargoes through membranes of live
cells. Since the first generations of CPPs suffered from insufficient cell and tissue selectivity …

Recent advances in selective and targeted drug/gene delivery systems using cell-penetrating peptides

SH Nam, J Park, H Koo - Archives of Pharmacal Research, 2023 - Springer
Biological cell membranes are a natural barrier for living cells. In the last few decades, the
cell membrane has been the main hurdle in the efficient delivery of bioactive and therapeutic …

Cell penetrating peptide: A potent delivery system in vaccine development

B Hasannejad-Asl, F Pooresmaeil… - Frontiers in …, 2022 - frontiersin.org
One of the main obstacles to most medication administrations (such as the vaccine
constructs) is the cellular membrane's inadequate permeability, which reduces their …

Applications and challenges for use of cell-penetrating peptides as delivery vectors for peptide and protein cargos

M Kristensen, D Birch, H Mørck Nielsen - International journal of …, 2016 - mdpi.com
The hydrophilic nature of peptides and proteins renders them impermeable to cell
membranes. Thus, in order to successfully deliver peptide and protein-based therapeutics …

Cell-penetrating peptides: a powerful tool for targeted drug delivery

DD Kotadiya, P Patel, HD Patel - Current Drug Delivery, 2024 - ingentaconnect.com
The cellular membrane hinders the effective delivery of therapeutics to targeted sites.
Cellpenetrating peptide (CPP) is one of the best options for rapidly internalizing across the …

[HTML][HTML] Potential of cell-penetrating peptides (CPPs) in delivery of antiviral therapeutics and vaccines

I Sadeghian, R Heidari, S Sadeghian, MJ Raee… - European Journal of …, 2022 - Elsevier
Viral infections are a great threat to human health. Currently, there are no effective vaccines
and antiviral drugs against the majority of viral diseases, suggesting the need to develop …

Delivery of various cargos into cancer cells and tissues via cell-penetrating peptides: a review of the last decade

A Shoari, R Tooyserkani, M Tahmasebi, DWPM Löwik - Pharmaceutics, 2021 - mdpi.com
Abstracts Cell-penetrating peptides (CPPs), also known as protein transduction domains,
are a class of diverse amino acid sequences with the ability to cross cellular membranes …

Recent in vivo advances in cell-penetrating peptide-assisted drug delivery

K Kurrikoff, M Gestin, Ü Langel - Expert opinion on drug delivery, 2016 - Taylor & Francis
Introduction: Delivery of macromolecular drugs is an important field in medical research.
However, macromolecules are usually unable to cross the cell membrane without the …