Angiogenic factors in preeclampsia: from diagnosis to therapy

SA Karumanchi - Hypertension, 2016 - Am Heart Assoc
Karumanchi Angiogenic Factors and Preeclampsia 1073 to as fenestrations. Although it was
previously known that VEGF induces endothelial fenestrae in culture, 38 experimental data …

Transcriptionally active syncytial aggregates in the maternal circulation may contribute to circulating soluble fms-like tyrosine kinase 1 in preeclampsia

A Rajakumar, AS Cerdeira, S Rana, Z Zsengeller… - …, 2012 - Am Heart Assoc
The cardinal manifestations of the pregnancy-specific disorder preeclampsia, new-onset
hypertension, and proteinuria that resolve with placental delivery have been linked to an …

Angiogenic factors and preeclampsia

ML Tjoa, RJ Levine… - Placent. Bed Disord. Basic …, 2010 - books.google.com
Preeclampsia is a systemic syndrome of pregnancy, which is characterized by widespread
maternal endothelial dysfunction [1]. It is a leading cause of maternal and neonatal morbidity …

The perinatal implications of angiogenic factors

GCS Smith, H Wear - Current Opinion in Obstetrics and …, 2009 - journals.lww.com
The perinatal implications of angiogenic factors : Current Opinion in Obstetrics and Gynecology
The perinatal implications of angiogenic factors : Current Opinion in Obstetrics and …

Angiogenic factors and preeclampsia

G Steinberg, EV Khankin, SA Karumanchi - Thrombosis Research, 2009 - Elsevier
Preeclampsia/eclampsia is a major cause of maternal and fetal morbidity worldwide.
Although the etiology of preeclampsia is still unclear, the clinical phenotypes of …

Preeclampsia and angiogenic imbalance

S Maynard, FH Epstein, SA Karumanchi - Annu. Rev. Med., 2008 - annualreviews.org
Preeclampsia is a systemic syndrome of pregnancy that originates in the placenta and is
characterized by widespread maternal endothelial dysfunction. Until recently, the molecular …

Disrupted balance of angiogenic and antiangiogenic signalings in preeclampsia

M Furuya, K Kurasawa, K Nagahama… - Journal of …, 2011 - Wiley Online Library
The placenta plays a central role in governing local circulatory system that mediates
maternal condition and fetal growth. In early gestational phases, the placenta exerts …

Elevated placental soluble vascular endothelial growth factor receptor-1 inhibits angiogenesis in preeclampsia

S Ahmad, A Ahmed - Circulation research, 2004 - Am Heart Assoc
Preeclampsia is an inflammatory disorder in which serum levels of vascular endothelial
growth factor (VEGF) and its soluble receptor-1 (sVEGFR-1, also known as sFlt-1) are …

Preeclampsia is associated with the presence of transcriptionally active placental fragments in the maternal lung

AJ Buurma, ME Penning, F Prins, JM Schutte… - …, 2013 - Am Heart Assoc
Preeclampsia is associated with increased levels of the circulating antiangiogenic factor sFlt-
1 and with an excessive shedding of placenta-derived multinucleated syncytial aggregates …

Angiogenic factors in superimposed preeclampsia: a longitudinal study of women with chronic hypertension during pregnancy

U Perni, C Sison, V Sharma, G Helseth, A Hawfield… - …, 2012 - Am Heart Assoc
Imbalances in circulating angiogenic factors contribute to the pathogenesis of preeclampsia.
To characterize levels of angiogenic factors in pregnant women with chronic hypertension …