Role of adhesion molecules in the homing and mobilization of murine hematopoietic stem and progenitor cells

M Vermeulen, F Le Pesteur… - Blood, The Journal …, 1998 - ashpublications.org
Bone marrow (BM) transplantation still must overcome multiple difficulties and should benefit
from better understanding of stem-cell homing and mobilization. Here, we analyzed the …

Homing and trafficking of hemopoietic progenitor cells

T Papayannopoulou, C Craddock - Acta haematologica, 1997 - karger.com
Investigations of the homing of transplanted hemopoietic cells into preconditioned recipients
have in most studies been referable to parameters that determine engraftment. The …

Hierarchy of molecular-pathway usage in bone marrow homing and its shift by cytokines

H Bonig, GV Priestley, T Papayannopoulou - Blood, 2006 - ashpublications.org
Efficient bone marrow (BM) homing is a prerequisite for successful engraftment of
transplanted hematopoietic cells (HPCs). Contradictory conclusions about the contribution of …

Molecular mechanisms underlying adhesion and migration of hematopoietic stem cells

AO Sahin, M Buitenhuis - Cell adhesion & migration, 2012 - Taylor & Francis
Hematopoietic stem cell transplantation is the most powerful treatment modality for a large
number of hematopoietic malignancies, including leukemia. Successful hematopoietic …

The VLA4/VCAM-1 adhesion pathway defines contrasting mechanisms of lodgement of transplanted murine hemopoietic progenitors between bone marrow and …

T Papayannopoulou, C Craddock… - Proceedings of the …, 1995 - National Acad Sciences
Selective lodgement or homing of transplanted hemopoietic stem cells in the recipient's
bone marrow (BM) is a critical step in the establishment of long-term hemopoiesis after BM …

Endothelial selectins and vascular cell adhesion molecule-1 promote hematopoietic progenitor homing to bone marrow

PS Frenette, S Subbarao, IB Mazo… - Proceedings of the …, 1998 - National Acad Sciences
The adhesive mechanisms allowing hematopoietic progenitor cells (HPC) homing to the
bone marrow (BM) after BM transplantation are poorly understood. We investigated the role …

Homing and mobilization in the stem cell niche

AD Whetton, GJ Graham - Trends in cell biology, 1999 - cell.com
All mature blood cells are derived from the haemopoietic stem cell (HSC). In common with
all other haemopoietic cells, stem cells are mobile, and it is this property of mobility that has …

PSGL-1 participates in E-selectin–mediated progenitor homing to bone marrow: evidence for cooperation between E-selectin ligands and α4 integrin

Y Katayama, A Hidalgo, BC Furie, D Vestweber… - Blood, 2003 - ashpublications.org
The nature and exact function of selectin ligands involved in hematopoietic progenitor cell
(HPC) homing to the bone marrow (BM) are unclear. Using murine progenitor homing …

Migration of human hematopoietic progenitor cells across bone marrow endothelium is regulated by vascular endothelial cadherin

JD van Buul, C Voermans, V van den Berg… - The Journal of …, 2002 - journals.aai.org
The success of stem cell transplantation depends on the ability of iv infused stem cells to
engraft the bone marrow, a process referred to as homing. Efficient homing requires …

Stem cell homing

JP Chute - Current opinion in hematology, 2006 - journals.lww.com
Several components of the essential process of stem cell homing have now been
characterized. Cell adhesion molecules and their ligands, extracellular matrix components …