Advances in the epidemiology, pathogenesis, and management of Cushing's syndrome complications

G Arnaldi, T Mancini, G Tirabassi, L Trementino… - Journal of …, 2012 - Springer
Cushing's syndrome (CS) is a clinical condition resulting from chronic exposure to
glucocorticoid excess. As a consequence, hypercortisolism contributes significantly to the …

Acute and life-threatening complications in Cushing syndrome: prevalence, predictors, and mortality

MH Schernthaner-Reiter, C Siess… - The Journal of …, 2021 - academic.oup.com
Context Cushing syndrome (CS) results in significant morbidity and mortality. Objective To
study acute and life-threatening complications in patients with active CS. Methods We …

Comorbidities in Cushing's disease

ST Sharma, LK Nieman, RA Feelders - Pituitary, 2015 - Springer
Introduction Cushing's disease is a rare disorder characterized by overproduction of ACTH
from a pituitary adenoma leading to hypercortisolemia that in turn leads to increased …

Long-Term Consequences of Cushing Syndrome: A Systematic Literature Review

S Puglisi, AME Perini, C Botto, F Oliva… - The Journal of Clinical …, 2024 - academic.oup.com
It is held that the condition of endogenous chronic hypersecretion of cortisol (Cushing
syndrome, CS), causes several comorbidities, including cardiovascular and metabolic …

Metabolic alterations and cardiovascular outcomes of cortisol excess

R Pivonello, MC De Martino, D Iacuaniello… - Cortisol excess and …, 2016 - karger.com
Cushing's syndrome (CS) is a severe chronic and systemic condition caused by
endogenous or exogenous excess of glucocorticoids, associated with increased morbidity …

[HTML][HTML] Cardiovascular complications of Cushings Syndrome: impact on morbidity and mortality

RN Clayton - Journal of Neuroendocrinology, 2022 - ncbi.nlm.nih.gov
Patients with Cushing's syndrome have increased morbidity and mortality from
cardiovascular causes, most commonly myocardial infarction and stroke, but also …

Cushing's syndrome: update on signs, symptoms and biochemical screening

LK Nieman - European journal of endocrinology, 2015 - academic.oup.com
Endogenous pathologic hypercortisolism, or Cushing's syndrome, is associated with poor
quality of life, morbidity, and increased mortality. Early diagnosis may mitigate against this …

Multisystem morbidity and mortality in Cushing's syndrome: a cohort study

OM Dekkers, E Horváth-Puhó… - The Journal of …, 2013 - academic.oup.com
Context: Cushing's syndrome (CS) is associated with hypercoagulability, insulin resistance,
hypertension, bone loss, and immunosuppression. To date, no adequately large cohort …

Mortality in Cushing's syndrome: systematic analysis of a large series with prolonged follow-up

G Ntali, A Asimakopoulou, T Siamatras… - European journal of …, 2013 - academic.oup.com
Objective In this study, we aim to assess the long-term survival and causes of death in a
retrospective cohort study on patients with all aetiologies of endogenous Cushing's …

Should we evaluate for cardiovascular disease in patients with Cushing's syndrome?

F Fallo, N Sonino - Clinical endocrinology, 2009 - Wiley Online Library
Current evidence indicates a strong association between Cushing's syndrome,
characterized by a cluster of systemic complications and increased cardiovascular risk. The …