Lactoferrin as protective natural barrier of respiratory and intestinal mucosa against coronavirus infection and inflammation

E Campione, T Cosio, L Rosa, C Lanna… - International Journal of …, 2020 - mdpi.com
Recently, the world has been dealing with a devastating global pandemic coronavirus
infection, with more than 12 million infected worldwide and over 300,000 deaths as of May …

Lactoferrin Against SARS-CoV-2: In Vitro and In Silico Evidences

E Campione, C Lanna, T Cosio, L Rosa… - Frontiers in …, 2021 - frontiersin.org
Lactoferrin (Lf) is a cationic glycoprotein synthetized by exocrine glands and is present in all
human secretions. It is also secreted by neutrophils in infection and inflammation sites. This …

Lactoferrin for COVID-19 prevention, treatment, and recovery

E Bolat, F Eker, M Kaplan, H Duman, A Arslan… - Frontiers in …, 2022 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), a unique beta-
coronavirus, has caused the most serious outbreak of the last century at the global level …

[HTML][HTML] The potential for Lactoferrin to reduce SARS-CoV-2 induced cytokine storm

M Zimecki, JK Actor, ML Kruzel - International immunopharmacology, 2021 - Elsevier
The COVID-19 pandemic is a serious global health threat caused by severe acute
respiratory syndrome of coronavirus 2 (SARS-CoV-2). Symptoms of COVID-19 are highly …

Lactoferrin as potential preventative and adjunct treatment for COVID-19

R Chang, TB Ng, WZ Sun - International Journal of Antimicrobial Agents, 2020 - Elsevier
ABSTRACT The coronavirus disease 2019 (COVID-19) pandemic is rapidly advancing
across the globe despite drastic public and personal health measures. Antivirals and …

The potential of lactoferrin, ovotransferrin and lysozyme as antiviral and immune-modulating agents in COVID-19

JK Mann, T Ndung'u - Future Virology, 2020 - Taylor & Francis
Coronavirus disease 2019 (COVID-19), caused by SARS coronavirus 2 (SARS-CoV-2), is
spreading rapidly with no established effective treatments. While most cases are mild, others …

Molecular mechanisms behind anti SARS-CoV-2 action of lactoferrin

M Miotto, L Di Rienzo, L Bò, A Boffi… - Frontiers in molecular …, 2021 - frontiersin.org
Despite the huge effort to contain the infection, the novel SARS-CoV-2 coronavirus has
rapidly become pandemic, mainly due to its extremely high human-to-human transmission …

Lactoferrin as antiviral treatment in COVID-19 management: preliminary evidence

E Campione, C Lanna, T Cosio, L Rosa… - International journal of …, 2021 - mdpi.com
Lactoferrin (Lf), a multifunctional cationic glycoprotein synthesized by exocrine glands and
neutrophils, possesses an in vitro antiviral activity against SARS-CoV-2. Thus, we conducted …

The biology of lactoferrin, an iron-binding protein that can help defend against viruses and bacteria

DB Kell, EL Heyden, E Pretorius - Frontiers in immunology, 2020 - frontiersin.org
Lactoferrin is a nutrient classically found in mammalian milk. It binds iron and is transferred
via a variety of receptors into and between cells, serum, bile, and cerebrospinal fluid. It has …

Ambulatory COVID-19 patients treated with lactoferrin as a supplementary antiviral agent: A preliminary study

L Rosa, G Tripepi, E Naldi, M Aimati… - Journal of clinical …, 2021 - mdpi.com
SARS-CoV-2, an enveloped, single-stranded RNA virus causing COVID-19, exerts morbidity
and mortality especially in elderly, obese individuals and those suffering from chronic …