Response to lysophosphatidic acid in Xenopus oocytes and its rapid desensitization: The role of Gq and Go G‐protein families

II Van‐Ham, M Lupu‐Meiri, M Tayer… - Journal of cellular …, 2004 - Wiley Online Library
Native Xenopus oocytes exhibit dose‐dependent depolarizing current responses to
lysophosphatidic acid (LPA), with EC50= 0.18 μM. Responses to LPA were subject to …

[HTML][HTML] G protein-activated K+ channels: a reporter for rapid activation of G proteins by lysophosphatidic acid in Xenopus oocytes

II Van-Ham, S Peleg, N Dascal, H Shapira, Y Oron - FEBS letters, 2004 - Elsevier
Threshold concentrations of lysophosphatidic acid (LPA) or acetylcholine (ACh) induce
pertussis toxin (PTX)-sensitive rapid desensitization of responses to LPA in Xenopus …

G protein‐activated K+ channels: a reporter for rapid activation of G proteins by lysophosphatidic acid in Xenopus oocytes

I Itzhaki Van-Ham, S Peleg, N Dascal, H Shapira… - FEBS …, 2004 - Wiley Online Library
Threshold concentrations of lysophosphatidic acid (LPA) or acetylcholine (ACh) induce
pertussis toxin (PTX)‐sensitive rapid desensitization of responses to LPA in Xenopus …

Direct voltage control of endogenous lysophosphatidic acid G‐protein‐coupled receptors in Xenopus oocytes

J Martinez‐Pinna, IS Gurung… - The Journal of …, 2010 - Wiley Online Library
Lysophosphatidic acid (LPA) G‐protein‐coupled receptors (GPCRs) play important roles in
a variety of physiological and pathophysiological processes, including cell proliferation …

Go G‐proteins mediate rapid heterologous desensitization of G‐protein coupled receptors in Xenopus oocytes

II Van‐Ham, Y Oron - Journal of cellular physiology, 2005 - Wiley Online Library
We have shown previously that responses to lysophosphatidic acid (LPA)
inXenopusoocytes exhibit pronounced rapid homologous desensitization mediated by Go …

Xenopus oocytes express multiple receptors for LPA-like lipid mediators

K Liliom, K Murakami-Murofushi… - … of Physiology-Cell …, 1996 - journals.physiology.org
In Xenopus laevis oocytes, both lysophosphatidic acid (LPA) and a cyclic phosphate-
containing analogue 1-acyl-sn-glycero-2, 3-cyclic phosphate (cLPA) isolated from Physarum …

Different signaling pathway between sphingosine‐1‐phosphate and lysophosphatidic acid in Xenopus oocytes: Functional coupling of the sphingosine‐1‐phosphate receptor to …

SJ Noh, MJ Kim, S Shim, JK Han - Journal of cellular …, 1998 - Wiley Online Library
In Xenopus oocytes, both sphingosine‐1‐phosphate (S1P) and lysophosphatidic acid (LPA)
activate Ca2+‐dependent oscillatory Cl− currents by acting through membrane‐bound …

Lysophosphatidic acid induces a pertussis toxin-sensitive Ca (2+)-activated Cl-current in Xenopus laevis oocytes

ME Durieux, MN Salafranca… - American Journal of …, 1992 - journals.physiology.org
Lysophosphatidic acid (LPA) induces a Ca (2+)-activated Cl-current in defolliculated
Xenopus laevis oocytes. The response appears mediated by a specific membrane receptor …

Phosphatidic acid and lysophosphatidic acid stimulate receptor-regulated membrane currents in the Xenopus laevis oocyte

JE Ferguson, MR Hanley - Archives of biochemistry and biophysics, 1992 - Elsevier
External application of dioleoyl-phosphatidic acid and oleoyl-lysophosphatidic acid
stimulated Ca 2+-dependent chloride currents in voltage-clamped Xenopus laevis oocytes …

Desensitization of inositol 1, 4, 5-trisphosphate/Ca2+-induced Cl− currents by prolonged activation of G proteins in Xenopus oocytes

MW Quick, HA Lester, N Davidson, MI Simon… - Journal of Biological …, 1996 - ASBMB
Expression of G protein α subunits of the G q family with various G protein-coupled receptors
induces activation of an inositol 1, 4, 5-trisphosphate (IP 3)/Ca 2+-mediated Cl …