The risk of lymph-node metastases in patients with high-grade dysplasia or intramucosal carcinoma in Barrett's esophagus: a systematic review

KB Dunbar, SJ Spechler - Official journal of the American College …, 2012 - journals.lww.com
OBJECTIVES: Endoscopic eradication therapy is used to treat mucosal neoplasms in
Barrett's esophagus, but cannot cure cancers that have metastasized to lymph nodes. The …

Is the risk of concomitant invasive esophageal cancer in high-grade dysplasia in Barrett's esophagus overestimated?

VJA Konda, AS Ross, MK Ferguson, JA Hart… - Clinical …, 2008 - Elsevier
Background & Aims: Recent studies have claimed long neoplasia-free survival rates with
endoscopic mucosal resection of high-grade dysplasia (HGD) in Barrett's esophagus (BE) …

Low prevalence of submucosal invasive carcinoma at esophagectomy for high-grade dysplasia or intramucosal adenocarcinoma in Barrett's esophagus: a 20-year …

VS Wang, JL Hornick, JA Sepulveda, R Mauer… - Gastrointestinal …, 2009 - Elsevier
BACKGROUND: The rate of occult adenocarcinoma at esophagectomy in patients with
Barrett's esophagus (BE) and high-grade dysplasia (HGD) has been reported to be …

Barrett esophagus and risk of esophageal cancer: a clinical review

SJ Spechler - Jama, 2013 - jamanetwork.com
Importance Barrett esophagus, a complication of gastroesophageal reflux disease (GERD),
predisposes patients to esophageal adenocarcinoma, a tumor that has increased in …

Predictors for neoplastic progression in patients with Barrett's esophagus: a prospective cohort study

M Sikkema, CWN Looman, EW Steyerberg… - Official journal of the …, 2011 - journals.lww.com
OBJECTIVES: Patients with Barrett's esophagus (BE) have an increased risk of developing
esophageal adenocarcinoma (EAC). As the absolute risk remains low, there is a need for …

Dysplasia in Barrett's esophagus: limitations of current management strategies

SJ Spechler - Official journal of the American College of …, 2005 - journals.lww.com
Dysplasia is a very imperfect biomarker for malignancy in Barrett's esophagus. Invasive
cancer has been found in 30–40% of esophagi resected because preoperative endoscopic …

Endoscopic versus surgical therapy for early cancer in Barrett's esophagus: a decision analysis

H Pohl, A Sonnenberg, S Strobel, A Eckardt… - Gastrointestinal …, 2009 - Elsevier
BACKGROUND: Esophagectomy for early esophageal adenocarcinoma is associated with
increased operative mortality and morbidity, but possibly a decreased recurrence rate …

Significance of neoplastic involvement of margins obtained by endoscopic mucosal resection in Barrett's esophagus

GA Prasad, NS Buttar, LM Wongkeesong… - Official journal of the …, 2007 - journals.lww.com
OBJECTIVES Although EMR has been used for elimination of neoplasia in BE, the
significance of positive carcinoma margins and depth of invasion on endoscopic resection …

Preoperative chemotherapy unmasks underlying Barrett's mucosa in patients with adenocarcinoma of the distal esophagus

J Theisen, HJ Stein, HJ Dittler, M Feith, C Moebius… - Surgical …, 2002 - Springer
Background Intestinal metaplasia of the distal esophagus frequently cannot be detected in
patients with esophageal adenocarcinoma. It has therefore been questioned whether …

Treatment of Barrett's esophagus with early neoplasia: a comparison of endoscopic therapy and esophagectomy

DB Schembre, JL Huang, OS Lin, N Cantone… - Gastrointestinal …, 2008 - Elsevier
BACKGROUND: Endoscopic therapies for early neoplasia in Barrett's esophagus may be a
viable alternative to esophagectomy. OBJECTIVE: Our purpose was to compare endoscopic …